摘要
目的 探讨阻塞性黄疸 (阻黄 )患者细胞因子的改变 ,从而揭示阻黄患者免疫功能的变化。方法 用ELISA方法检测 3 6例阻塞性黄疸患者术前及术后可溶性白细胞介素Ⅱ受体 (sIL 2R)、肿瘤坏死因子 (TNF α)、白细胞介素Ⅵ (IL 6)及白细胞介素Ⅷ (IL 8)的水平。结果 术前阻塞性黄疸患者的sIL 2R、TNF α、IL 6及IL 8水平均明显高于正常人 (P <0 .0 1) ;解除胆道梗阻术后 ,各细胞因子水平开始下降 ,至术后第 14天接近正常水平。结论 解除黄疸有助于患者免疫功能的恢复 ,联合检测细胞因子在阻塞性黄疸患者中具有重要的临床意义。
HT6”,5”] Objective [WT5”BZ]To study the change of immunologic function of the patient with obstructive jaundice. [WT5”HZ]Methods [WT5”BZ]The level of the sIL 2R, TNF α, IL 6 and IL 8 in 36 cases of obstructive jaundice before and after operation were measured. [WT5”HZ]Results [WT5”BZ]The level of the sIL 2R, TNF α, IL 6 and IL 8 in 36 cases of obstructive jaundice before operation was higher than normal control group ( P <0.01). It decreased after the obstruction was removed, and it was close to normal control on 14th day after operation. [WT5”HZ]Conclusion [WT5”BZ]The result suggest that relief of jaundice could improve the immunologic function of the patient.
出处
《中国普外基础与临床杂志》
CAS
2000年第3期170-171,共2页
Chinese Journal of Bases and Clinics In General Surgery
