摘要
目的比较右旋美托咪啶和可乐定对硬膜外麻醉妇科手术患者的影响。方法硬膜外麻醉下行阴道式子宫切除术成年女性患者100例,随机均分成2组:罗哌卡因+右旋美托咪啶组(RD组)和罗哌卡因+可乐定组(RC组)。RD组给予0.75%罗哌卡因17 mL+右旋美托咪啶(1.5μg/kg),RC组0.75%罗哌卡因17 mL+可乐定(2μg/kg)。分析镇痛开始时间、感觉及运动阻滞平面及时间、镇静评分和术中术后不良反应。结果 RD组的镇静评分优于RC组;RD组的罗哌卡因用量少于RC组;2组恶心和口干发生率稍高。结论右旋美托咪啶比可乐定更适宜作为硬膜外麻醉的辅助药物。
Objective To compare the effects of dexmedetomidine and clonidine on the patients receiving gynecologic surgery under epidural anesthesia.Methods A total of 100 adult female patients undergoing vaginal hysterectomies under epidural anesthesia were randomly divided into ropivacaine plus dexmedetomidine（RD） group（n=50） and ropivacaine plus clonidine（RC） group（n=50）.RD group received 0.75% epidural ropivacaine 17 mL and dexmedetomidine1.5 μg/kg,while RC group received admixture of 17 mL 0.75% ropivacaine and 2 μg/kg clonidine.The time of analgesia,the levels and duration of sensory and motor block,the sedation score,and postoperative adverse reactions were observed.Results Sedation scores were higher in the RD group than in the RC group.The ropivacaine dose was less in the RD group than in RC group.The adverse reactions were a slightly higher incidence of nausea and dry mouth in both groups.Conclusion Dexmedetomidine is a better adjuvant of anesthesia compared with clonidine for epidural anesthesia.
出处
《实用临床医药杂志》
CAS
2012年第5期85-87,共3页
Journal of Clinical Medicine in Practice
