摘要
目的:通过对功能性核磁共振成像(fMRI)技术下针刺神门穴和大陵穴激活不同脑功能区的观察,探讨两穴效应的相对特异性。方法:纳入右利手健康志愿者10例,分别针刺受试者的右侧神门和大陵穴,在fMRI下采用组块刺激模式进行扫描,所获得数据通过Matlab软件SPM5模块分析,观察两穴的脑激活区。结果:针刺神门穴主要激活的brodmann分区为:左侧BA10、BA13、BA47、BA22;右侧BA40、BA44。针刺大陵穴主要激活的brodmann分区为:左侧BA46、BA47、BA22、BA10、BA45;右侧BA44、BA9、BA6、BA40。结论:针刺神门穴与大陵穴激活的脑功能区不完全相同,两穴共同激活区为语言、认知功能等相关区域;神门穴特异激活情绪控制等区域,大陵穴特异激活自主神经功能支配等区域,两穴针刺效应各具特异性。
Objective To observe the effect of acupunture at Shenmen（HT 7） and Daling（PC 7） on different cerebral functional regions by Functional Magnetic Resonance Imaging（fMRI）,and discuss the relative specificity of effect of these two acupoints.Methods Ten healthy right-handed volunteers were enrolled in this research.Under the scan of fMRI with the pattern of ＂rest-stimulation-rest-stimulation-rest＂,acupuncture stimulation was given at Shenmen（HT 7） and Daling（PC 7） on the right side,and all the data were analyzed with Matlab software and SPM5 package to observe the activated cerebral regions.Results The activated brodmann areas by acupuncture at Shenmen（HT 7） were mainly BA10、BA13、BA47、BA22 on the left side and BA40、BA44 on the right side,while the activated areas by acupunoture at Daling（PC 7） were BA46、BA47、BA22、BA10、BA45 on the left side and BA44、BA9、BA6、BA40 on the right side.Conclusion The activated cerebral functional regions of acupuncture stimulation at Shenmen（HT 7） and Daling（PC 7） are not exactly the same,which indicates that the acupuncture effects of the two acupoints are specific.With the same activated areas of language and cognitive function,the Shenmen（HT 7） specializes in emotion control while the Daling（PC 7） could active the autonomic nerve function area.
出处
《中国针灸》
CAS
CSCD
北大核心
2012年第4期325-328,共4页
Chinese Acupuncture & Moxibustion
关键词
功能性磁共振成像
穴
神门
穴
大陵
脑功能区
Functional Magnetic Resonanse Imaging（fMRI）
Point HT 7（Shenmen）
Point PC 7（Daling）
Functional Area of Brain
