摘要
通过测定冷驯化(5℃)到脱冷驯化(30℃)条件下,大绒鼠(Eothenomys miletus)的体重、摄入能、静止代谢率(RMR)、非颤抖性产热(NST)和血清瘦素含量等参数,探讨了血清瘦素浓度与能量收支的关系。结果表明,冷驯化可致大绒鼠体重下降,RMR、NST、摄入能升高,血清瘦素浓度降低;脱冷驯化后大绒鼠体重增加,RMR、NST、摄入能降低,血清瘦素浓度增加。血清瘦素含量与体重呈正相关,与RMR、NST、摄入能呈负相关。表明大绒鼠的体重、摄入能和产热能力具有较强的可塑性,且瘦素可能参与了大绒鼠适应冷驯化及恢复过程中的能量平衡和体重的调节。
In order to study effects of serum leptin level on energy metabolism, we measured body mass, serum leptin levels, energy intake, rest metabolic rate （RMR）, nonshivering thermogenesis （NST） in Eothenomys miletus under cold acclimation （5℃） or rewarming （30℃）. Cold acclimation induced increases in RMR, NST, energy intake. Those measurements decreased after rewarming. Body mass, serum leptin levels decreased during cold acclimation treatment and increased after rewarming. Serum leptin levels were positively correlated with body mass and negatively correlated with RMR, NST and energy intake. These results suggest that body mass, energy intake, thermogenic Capacity in E. miletus has a strong phenotypic plasticity. Serum leptin participated in the regulation of energy balance and body mass in E. miletus during cold acclimation and rewarming.
出处
《动物学杂志》
CAS
CSCD
北大核心
2012年第2期120-126,共7页
Chinese Journal of Zoology
基金
国家自然科学基金项目(No.31071925)
云南省教育厅科研基金重大专项项目(No.ZD2009007)
云南省应用基础研究计划项目(No.2011FZ082
2008ZC043M)
关键词
大绒鼠
血清瘦素
冷驯化
脱冷驯化
Eothenomys miletus
Serum leptin
Cold acclimation
Rewarming
