期刊文献+

富血小板血浆修复骨缺损的机制研究进展 被引量:11

Research progress of the mechanism of repairing bone defect with PRP
暂未订购
导出
摘要 富血小板血浆(platelet-rich plasma,PRP)是含有高浓度血小板的血浆,其中含丰富的生长因子,广泛应用于口腔颌面外科、骨科,用于骨组织、软骨组织和软组织的修复,其中生长因子对骨修复的多个阶段和多个方面都起作用,以血小板衍化生长因子(PDGF)和转化生长因子-β(TGF-β)的作用最为显著,机制研究也较为透彻。 Platelet-rich plasma(PRP) is a kind of plasma with high concentration of platelet,which includes a lot of growth factors. It was widely used in oral and maxillofacial surgery and orthopedics,for the repairing of bone,cartilage and soft tissues. The growth factors,especially PDGF and TGF-β,plays an important role in different stages and aspects.
出处 《中国骨伤》 CAS 2012年第3期258-261,共4页 China Journal of Orthopaedics and Traumatology
基金 浙江省自然科学基金资助项目(编号:Y2110448)~~
关键词 血小板 血浆 综述文献 Blood platelets Plasma Review literature
  • 相关文献

参考文献32

  • 1Marx RE,Carlson ER,Eichstaedt RM,et al.Platelet rich plasma:Growth factor enhancement for bone grafts[J].Oral Surg Oral Med Oral Pathol Oral Radiol Endod,1998,85(6):638-646.
  • 2Jungbluth P,Wild M,Grassmann JP,et al.Platelet rich plasma on calcium phosphate granules promotes metaphyseal bone healing in mini pigs[J].J Orthop Res,2010,28(11):1448-1455.
  • 3Scala M,Gipponi M,Mereu P,et al.Regeneration of mandibular os-teoradionecrosis defect with platelet rich plasma gel[J].In Vivo,2010,24(6):889-893.
  • 4Dallari D,Savarino L,Stagni C,et al.Enhanced tibial osteotomy healing with use of bone grafts supplemented with platelet gel or platelet gel and bone marrow stromal cells[J].J Bone Joint Surg Am,2007,89(11):2413-2420.
  • 5Kanthan SR,Kavitha G,Addi S,et al.Platelet rich plasma(PRP)enhances bone healing in non united critical sized defects:a pre-liminary study involving rabbit models[J].Injury,2011,42(8):782-789.
  • 6张洪涛,蔡道章,刘康,李青,曾毅军.富血小板血浆对人骨髓间充质干细胞成骨诱导的影响[J].中国组织工程研究与临床康复,2009,13(6):1045-1048. 被引量:16
  • 7Baeyens W,Glineur R,Evrard L.The use of platelet concentrates:platelet rich plasma(PRP)and platelet rich fibrin(PRF)in bone reconstruction prior to dental implant surgery[J].Rev Med Brux,2010,31(6):521-527.
  • 8Antczak AJ,Vieth JA,Singh N,et al.Internalization of IgG-coated targets results in activation and secretion of soluble CD40ligand and RANTES by human platelets[J].Clin Vaccine Immunol,2011,18(2):210-216.
  • 9张爱民,张英泽,马维,范志勇,史正亮,宋永周,张华,郑广德.血小板浓缩液的制备及促进兔尺骨骨折愈合方面的实验研究[J].中国骨伤,2005,18(6):346-348. 被引量:3
  • 10Kreja L,Brenner RE,Tautzenberger A,et al.Non resorbing osteo-clasts induce migration and osteogenic differentiation of mes-enchymal stem cells[J].J Cell Biochem,2010,109(2):347-355.

二级参考文献71

共引文献38

同被引文献165

引证文献11

二级引证文献66

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部