摘要
目的:研究毛茛科植物黄连Coptis chinensis的化学成分。方法:利用柱色谱、凝胶柱色谱、高效液相色谱等各种色谱技术对黄连的95%进行分离,根据其所得化合物的理化性质与UV,IR,MS,NMR等光谱数据鉴定其结构。结果:从黄连的95%乙醇提取物的氯仿萃取部分分离得到7个已知成分,分别鉴定为香草酸(1),落叶松树脂醇(2),原儿茶酸乙酯(3),小檗碱(4),丹参素甲酯(5),反式阿魏酰基酪胺(6),氧化小檗碱(7)。结论:其中,化合物(3),(5),(6)为首次从该属植物中分离得到。
Objective：Aim To study the chemical constituents of Co.chinensis Franch.Method： The compounds were separated and purified by column chromatography and their structures were established by spectroscopic methods.Result： Seven compounds were isolated from the chloroform extract of C.chinensis Franch,whose structures were determined as（1）,vanillic acid（1）,lariciresinol（2）,protocatechuic acid ethyl ester（3）,berberine（4）,3,4,α-trihydroxy-methyl phenylpropionate（5）,N-tran-feruloyltyramine（6）,Oxyberberine（7）.Conclusion： Compounds 3,5,6were isolated from this genus for the first time.
出处
《中国实验方剂学杂志》
CAS
北大核心
2012年第7期74-76,共3页
Chinese Journal of Experimental Traditional Medical Formulae
基金
国家自然科学基金项目(30873368)
关键词
结构鉴定
柱色谱法
黄连
氯仿提取物
structural identification
column chromatography
Coptis chinensis
chloroform extract
