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神经干细胞移植在创伤性脑损伤再生与修复中的作用和影响因素 被引量：8

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摘要 创伤性脑损伤（traumatic brain injury,TBI）是一种十分常见的神经外科疾病,世界卫生组织研究表明,到2020年创伤性脑损伤将成为死亡和致残的主要疾病^[1,2]。每年大约有1 000万人遭受创伤性脑损伤,其中主要集中在15－24岁的年轻人和75岁以上的老年人。TBI后神经细胞受损、缺失或死亡,常使神经功能严重受损而导致偏瘫、失语、智力障碍或昏迷,甚至死亡。
作者 贺晓生
机构地区 第四军医大学西京医院神经外科
出处 《中华神经外科疾病研究杂志》 CAS 2012年第1期1-3,共3页 Chinese Journal of Neurosurgical Disease Research
基金 国家自然科学基金资助项目(30971173)
关键词 NSCS 组织工程 TBI 再生与修复
分类号 R318 [医药卫生—生物医学工程]
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参考文献10

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  • 2Bozkurt G,Mothe AJ,Zahir T,et al.Chitosan channels containingspinal cord-derived stem/progenitor cells for repair of subacute spinalcord injury in the rat[J].Neurosurgery,2010,67(6):1733-1744.
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  • 5张赛,刘晓智.干细胞移植救治颅脑创伤的再思考[J].中华神经外科疾病研究杂志,2009,8(2):97-100. 被引量：3
  • 6Bozkurt G,Mothe AJ,Zahir T,et al.Chitosan channels containingspinal cord-derived stem/progenitor cells for repair of subacute spinalcord injury in the rat[J].Neurosurgery,2010,67(6): 1733-1744.
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二级参考文献26

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  • 7Ni HT, Hu S, Sheng WS, et al. High-level expression of functional chemokine receptor CXCR4 on human neural precursor cells [ J ]. Brain Res Dey Brain Res, 2004, 152(2) : 159 -169.
  • 8Son BR, Marquez-Curtis LA, Kucia M, et al. Migration of bone manow and cord blood mesenchymal stem cells in vitro is regulated by stromal-derived factor-1-CXCR4 and hepatocyte growth factor-c-met axes and involves matrix metalloproteinases [ J]. Stem Cells, 2006, 24 (5) : 1254 -1264.
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共引文献2

同被引文献27

引证文献8

二级引证文献26

中华神经外科疾病研究杂志
2012年 第1期

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