摘要
超声波最优化法提取溪黄草总黄酮,提取物经乙酸乙酯萃取后进行柱层析分离纯化,得一纯物质,鉴定为黄酮化合物,并以该化合物为配体合成了锌(Ⅱ)、铜(Ⅱ)和铁(Ⅲ)配合物,研究它们对亚硝化反应的抑制作用。结果表明该黄酮化合物及其配合物在一定浓度范围能阻断亚硝胺的合成及清除亚硝酸盐,其中配合物作用较黄酮配体强。
The optimum ultrasonic extraction conditions were used to extract the total flavonoids in Rabdosia serra （Maxim.） Hara. The flavonoids were extracted by ethyl acetate and further purified by chromatography on silica gel. The type of the pure flavonoid was identified and its Cu（Ⅱ）, Zn（Ⅱ）, Fe（Ⅲ） complexes were synthesized. Their inhibition of nitrosation was tested. The results showed that the flavone and its complexes could inhibit nitrosodimethylamine synthesis and eliminate sodium nitrite, and the complexes showed stronger inhibition effect than the flavone.
出处
《化学世界》
CAS
CSCD
北大核心
2012年第3期172-175,共4页
Chemical World
关键词
溪黄草
黄酮
配合物
抑制亚硝化
Rabdosia serra （Maxim.） Hara
flavonoid
complexes
inhibition on nitrosation
