期刊文献+

深低温停循环顺灌脑保护在主动脉手术中的应用 被引量:1

DEEP HYPOTHERMIA STOP-CIRCULATION SEQUENTIAL IRRIGATION BRAIN PROTECTION USED IN OPERATION OF AORTA
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摘要 目的探讨深低温停循环在主动脉手术中应用的安全时限及更优脑保护方案。方法选择2009年1月~2012年1月深低温停循环(Deep Hypothermic Circulatory Arrest,DHCA)应用于主动脉手术12例,全身麻醉,PH稳态体外循环管理,降温至鼻咽温16℃停止循环,手术操作完毕后,恢复循环,复温至鼻咽温37℃脱离体外循环。8例经股动脉灌注,4例经右腋动脉灌注,经腔房管回流,心脏停跳液灌注经左右冠状动脉开口选择性灌注。结果术中最低鼻咽温14.3~17.3℃(15.9±2.7℃),体外循环时间223~412 min(296.9±54.3 min),主动脉阻断时间102~231 min(174.2±39.3 min)。深低温停循环下选择性脑灌注时间37~153 min(73.2±42.2 min)。1例患者术中主动脉夹层急性破裂死亡,1例患者因渗血延迟关胸于72 h后关胸,未发生中枢神经系统并发症、肾功不全、截瘫等。结论深低温停循环技术是大血管及复杂紫绀型先心病手术的重要生命支持技术,采用PH稳态进行体外循环管理可行,4例经右腋动脉行顺行选择性脑灌注(Antegrade Selective Cerebral Perfusion,ASCP)取得良好效果,余7例停循环时间短未行脑选择性灌注并无脑部并发症,证明DHCA仍是脑保护的基本技术。
出处 《现代医院》 2012年第3期43-44,共2页 Modern Hospitals
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