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舍曲林合并心理治疗对青少年抑郁的疗效研究 被引量:6

Efficacy of sertraline combined with psychotherapy on juvenile depression
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摘要 目的探讨舍曲林合并个别心理治疗对青少年抑郁症的疗效。方法将132例青少年抑郁症患者随机分为2组:舍曲林治疗组(药物组)、舍曲林合并心理治疗组(综合组),分别采用汉密尔顿抑郁量表(HAMD)、贝克抑郁自评问卷(BDI)在治疗前、治疗4周末、8周末进行评定。结果两组治疗4周末和8周末的HAMD、BDI评分均显著降低(P<0.01),但以综合组下降明显。综合组在治疗4周末和8周末的BDI评分与对照组相比,差异有统计学意义(P<0.01);综合组在8周末的HAMD评分与4周末相比,差异有统计学意义(P<0.01)。结论舍曲林合用心理治疗对青少年抑郁症的疗效优于单用舍曲林。家长教育是对青少年心理治疗的一种有益尝试。 Objective To explore the curative effects of sertraline combined with psychotherapy on juvenile depression.Methods 132 patients with juvenile depression were randomly divided into two groups:integrated group(treated with sertraline combined with psychotherapy)and drug group(treated with sertraline alone).The curative effects were evaluated on the basis of HAMD,BDI scores after 4 weeks and 8 weeks of treatment.Results HAMD,BDI scores two groups decreased at the end of 4 and 8 weeks respectively(P0.01);the differences in BDI scores between the two groups were significant at the end of 4 and 8 weeks respectively;at the end of 8 weeks,HAMD score of Integrated group was significant lower than that at the end of 4 weeks.Conclusion Effect of sertraline combined with psychotherapy on juvenile depression is better than that of sertraline,and parental education is a good try for treating juvenile depression.
出处 《实用药物与临床》 CAS 2012年第3期145-147,共3页 Practical Pharmacy and Clinical Remedies
关键词 心理治疗 舍曲林 青少年抑郁症 Psychotherapy Sertraline Juvenile depression
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