摘要
干眼是常见的眼科疾病，与泪膜功能紊乱息息相关。泪膜由脂质层、水液层及黏蛋白层（或脂质层、水合黏蛋白层）组成。脂质层成分来源于睑板腺，瞬目时分布于泪膜表面，具有减少泪液蒸发速率，稳定泪膜结构等生理功能，在维持眼表健康中发挥重要作用。脂质缺乏的患者脂质层厚度变薄、质量下降、分布不均，引起干眼的症状。含脂质的人工泪液在补充水液的同时补充泪膜脂质成分，有效的增加脂质层厚度、维持泪膜稳定、改善睑板腺功能、促进泪膜分布，具有良好的治疗效果。
Dry eye is a common disease in the ophthalmological clinic, which is related to the dysfunction of tear film. The tear film is composed of lipid layer, aqueous layer and mucin layer （ or lipid layer, aqueous/mucin layer）. The lipid of the outmost layer derived from Meibomian gland and distributed on the tear film after blinking can decrease the evaporation and stabilize the tear film. The thickness, quality, and distribution of lipid layer are impaired in many dry eye patients, hence restoring the physiological function of lipid layer may be crucial for the treatment of this kind of dry eye. The lipid artificial tears manifest great effects on increasing lipid layer thickness, stabilizing tear film, improving Meibomian gland dysfunction, and promoting tear film distribution.
出处
《中华眼科杂志》
CAS
CSCD
北大核心
2012年第3期282-285,共4页
Chinese Journal of Ophthalmology
关键词
干眼病
眼药水
脂类
睑板腺
Xerophthalmia
Ophthalmic solutions
Lipid
Meibomian gland
