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Syntheses and Crystal Structures of 3-Chloro-N'-(3,5-dichloro-2-hydroxybenzylidene)-benzohydrazide and Its Oxovanadium(V) Complex with Antimicrobial Activity

Syntheses and Crystal Structures of 3-Chloro-N'-(3,5-dichloro-2-hydroxybenzylidene)-benzohydrazide and Its Oxovanadium(V) Complex with Antimicrobial Activity
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摘要 A hydrazone compound 3-chloro-N'-(3,5-dichloro-2-hydroxybenzylidene)benzo-hydrazide(H2L) derived from the condensation of 3,5-dichlorosalicylaldehyde with 3-chloro-benzohydrazide and its oxovanadium(V) complex [VOL(CH3OH)(OCH3)] have been successfully prepared and characterized by physico-chemical methods and single-crystal X-ray diffraction.The hydrazone ligand coordinates to the V atom through the phenolate O,imine N,and enolic O atoms.The V atom is hexa-coordinated in a distorted octahedral geometry.The antimicrobial activities(MIC) of the hydrazone ligand and the oxovanadium(V) complex have been evaluated against the bacteria Staphylococcus aureus,Baccilus subtilis,Pseudomonas aeruginosa,and Escherichia coli. A hydrazone compound 3-chloro-N'-(3,5-dichloro-2-hydroxybenzylidene)benzo-hydrazide(H2L) derived from the condensation of 3,5-dichlorosalicylaldehyde with 3-chloro-benzohydrazide and its oxovanadium(V) complex [VOL(CH3OH)(OCH3)] have been successfully prepared and characterized by physico-chemical methods and single-crystal X-ray diffraction.The hydrazone ligand coordinates to the V atom through the phenolate O,imine N,and enolic O atoms.The V atom is hexa-coordinated in a distorted octahedral geometry.The antimicrobial activities(MIC) of the hydrazone ligand and the oxovanadium(V) complex have been evaluated against the bacteria Staphylococcus aureus,Baccilus subtilis,Pseudomonas aeruginosa,and Escherichia coli.
作者 高栓平
出处 《Chinese Journal of Structural Chemistry》 SCIE CAS CSCD 2012年第3期377-384,共8页 结构化学(英文)
基金 supported by the Key Program of the Baoji University of Arts and Sciences (No. ZK1018)
关键词 hydrazone oxovanadium complex crystal structure synthesis antimicrobial activity hydrazone oxovanadium complex crystal structure synthesis antimicrobial activity
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