摘要
目的:比较丁螺环酮与氯硝西泮治疗广泛性焦虑症的疗效及副反应。 方法:符合CCMD2R广泛性焦虑症诊断标准的门诊及住院病人70例,平分为2组,完成6周的治疗观察,于治疗前及治疗后1、3、6周末用汉密尔顿焦虑量表(HAMA)和不良反应症状量表(TESS)评定疗效和副作用。 结果:丁螺环酮治疗广泛性焦虑症的疗效与氯硝西泮相似,但副作用比氯硝西泮小。 结论:丁螺环酮治疗广泛性焦虑症的疗效确切。
Objective:The purpose of this study was to investigate the clinical efficacy and the side effects of buspirone in the treatment of general anxiety disorder. Method:70 patients who met CCMD 2 R criteria for general anxiety disorder were involved in this study, they were randomly assigned to buspirone group (n=35) and clonopin group (n=35) for six weeks. Effects and side reactions were evaluated with hamilton anxiety scale (HAMA) and treatment emergent symptoms scale (TESS) before and after treatment . Results:The therapeutic efficacy in buspirone group was similar to that in clonopin (P>0 05),however the side effects of buspirone were lighter than clonopin. Conclusion:The stuey suggests that buspirone is effective in the treatment of general anxiety disorder and produces fewer side effects.
出处
《临床精神医学杂志》
2000年第1期20-21,共2页
Journal of Clinical Psychiatry