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丁螺环酮治疗广泛性焦虑症临床对照研究 被引量:35

A clinical control study of buspirone in the treatment of general anxiety disorder
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摘要 目的:比较丁螺环酮与氯硝西泮治疗广泛性焦虑症的疗效及副反应。 方法:符合CCMD2R广泛性焦虑症诊断标准的门诊及住院病人70例,平分为2组,完成6周的治疗观察,于治疗前及治疗后1、3、6周末用汉密尔顿焦虑量表(HAMA)和不良反应症状量表(TESS)评定疗效和副作用。 结果:丁螺环酮治疗广泛性焦虑症的疗效与氯硝西泮相似,但副作用比氯硝西泮小。 结论:丁螺环酮治疗广泛性焦虑症的疗效确切。 Objective:The purpose of this study was to investigate the clinical efficacy and the side effects of buspirone in the treatment of general anxiety disorder. Method:70 patients who met CCMD 2 R criteria for general anxiety disorder were involved in this study, they were randomly assigned to buspirone group (n=35) and clonopin group (n=35) for six weeks. Effects and side reactions were evaluated with hamilton anxiety scale (HAMA) and treatment emergent symptoms scale (TESS) before and after treatment . Results:The therapeutic efficacy in buspirone group was similar to that in clonopin (P>0 05),however the side effects of buspirone were lighter than clonopin. Conclusion:The stuey suggests that buspirone is effective in the treatment of general anxiety disorder and produces fewer side effects.
作者 朱跃华
出处 《临床精神医学杂志》 2000年第1期20-21,共2页 Journal of Clinical Psychiatry
关键词 广泛性 焦虑症 下螺环酮 氯硝西泮 治疗 General anxiety disorder Buspirone Clonopin
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二级参考文献3

  • 1张明园,精神科评定量表手册,1993年,134,38,151页
  • 2张明园,精神科评定量表手册,1993年,198页
  • 3团体著者,中国精神疾病分类方案与诊断标准(第2版),1989年,54页

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