摘要
目的探讨妊娠期高血压疾病(HDCP)患者肝肾功能指标监测的临床意义。方法分析109例HDCP患者(包括妊娠高血压组、轻度子痫前期组和重度子痫前期组)和66例健康妊娠组的初诊建卡时及孕末期血清尿素氮(BUN)、肌酐(Cr)、尿酸(UA)、谷丙转氨酶(ALT)和谷草转氨酶(AST)等指标,了解其变化情况及与HDCP的关联性。结果各组间孕末期UA值均显著高于初诊建卡时。与健康妊娠组相比,重度子痫前期组孕末期UA值和Cr值改变显著(P<0.01)。各组间孕末期BUN、ALT和AST指标变化也无显著差异(P>0.05)。结论在HDCP孕妇的肝肾功能各项指标中,血清UA对于预测HDCP的发展意义最显著。
Objective To explore significance of the variation of renal and liver function in the patients with hypertensive disorder complicating pregnancy（HDCP）. Methods An analysis of 109 cases of pregnancy with HDCP and 66 cases of normal pregnancy on value of serum urea nitrogen （BUN）, creatinine （Cr）, uric acid （UA）, cereal third transaminase （ALT） and aspertate aminotransferase （AST） between the first visit and the third trimester, understand the changes and association with HDCP. Results UA value of each group in the third trimester was significantly higher than that in first visit. For the changes of UA and Cr values, there were significant difference between the normal group and severe preeclampsia group of the third trimester （P〈0.01）. At the third trimester, there is no obvious difference of BUN, ALT and AST between each group. Conclusion Among the liver and kidney function measurements, serum UA value is more significant for predicting the development of the HDCP.
出处
《世界临床药物》
CAS
2012年第3期163-166,共4页
World Clinical Drug
关键词
妊娠期高血压疾病
肝功能
肾功能
尿酸(UA)
hypertensive disorder complicating pregnancy
liver function
renal function
uric acid （UA）
