摘要
目的探讨从医院感染患者中分离的革兰阴性杆菌分布及耐药性,为治疗医院感染患者提供依据。方法收集2010年285例住院患者医院感染革兰阴性杆菌的相关资料进行回顾性分析。结果共检出革兰阴性杆菌305株,主要为铜绿假单胞菌、大肠埃希菌、肺炎克雷伯菌、鲍氏不动杆菌、嗜麦芽寡养单胞菌和阴沟肠杆菌;肠杆菌科细菌对亚胺培南和美罗培南的耐药率为1.4%和2.0%;铜绿假单胞菌对亚胺培南、美罗培南的耐药率为34.0%、32.1%;鲍氏不动杆菌对亚胺培南、美罗培南的耐药率为28.9%和31.1%。结论亚胺培南和美罗培南对肠杆菌科仍保持高活性,但鲍氏不动杆菌、铜绿假单胞菌的耐药性已增加,应予以重视。
OBJECTIVE To investigate the species,distribution and resistance of gram-negative bacilli causing nosocomial infections,so as to guide management.METHODS The related data of 285 patients with nosocomial infections in 2010 were retrospectively analyzed.RESULTS A total of 305 gram-negative bacilli were isolated,the most common pathogens were Pseudomonas aeruginosa,Escherichia coli,Klebsiella pneumoniae,Acinetobacter baumannii,Stenotrophomonas maltophilia,and Enterobacter cloacae.The drug resistant rates of Enterobacteriaceae against imipenem and meropenem were 1.4% and 2.0% respectively.The drug resistant rates of P.aeruginosa against imipenem and meropenem were 34.0% and 32.1%,respectively.The drug resistant rates of A.baumannii against imipenem and meropenem were 28.9% and 31.1%.CONCLUSION Imipenem and meropenem remain highly active against Enterobacteriaceae,while the drug resistant rates of both A.baumannii and P.aeruginosa have increased,and which should be paid attention to.
出处
《中华医院感染学杂志》
CAS
CSCD
北大核心
2012年第6期1262-1264,共3页
Chinese Journal of Nosocomiology
关键词
医院感染
革兰阴性杆菌
药敏试验
耐药性
Nosocomial infection
Gram-negative bacillus
Drug susceptibility test
Drug resisitance
