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采用自体血回输与血库血输入对输卵管妊娠破裂手术后疗效及感染的对比研究 被引量:5

Effect and infection between use of autologous blood transfusion and homologous blood transfusion after surgery for ruptured tubal pregnancy
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摘要 目的对比采用自体血回输与血库血输入对输卵管妊娠破裂手术的疗效及感染。方法考察并对比输卵管妊娠破裂手术后,31例血库血输入和38例自体血回输的术后疗效和感染情况。结果与血库血输入组比,自体血回输组输血前的C-反应蛋白(CPR)、中性粒细胞,差异无统计学意义;血库血输入组输血前CPR为(2.64±1.08)mg/L,与输血后1h、术后1、2d的CPR(15.50±5.60)、(2.64±1.08)、(93.80±16.40)mg/L比较,差异均有统计学意义(均P<0.05);自体血回输组输血前的CPR为(3.00±1.05)mg/L,与输血后1h、术后1、2d的CPR(12.50±2.40)、(84.60±21.20)、(70.10±30.40)mg/L比较,差异均有统计学意义(均P<0.05),血库血输入组术后2d的CPR与术后1d比,有降低趋势,但差异无统计学意义,术后2d自体血回输组的CPR显著降低,差异有统计学意义(P<0.05);与血库血输组比,自体血回输组输血后1h、术后1d和2d的CPR较低;与输血前比,血库血输入组和自体血回输组输血后1h、术后1、2d的中性粒细胞显著增高,差异均有统计学意义(均P<0.05);与术后1d比,自体血回输组术后2d的中性粒细胞显著降低;与血库血输入组比,自体血回输组的输血后1h、术后1d和术后2d的中性粒细胞显著较低;与输血前比,血库血输入组和自体血回输组输血后1h、术后1d的血红蛋白显著降低,差异均有统计学意义(均P<0.05);与术后1d比,血库血输入组术后2d的血红蛋白有增高趋势;与术后1d比,血库血输入组术后2d的血红蛋白增高至输血前水准,差异均无统计学意义。结论自体血回输有利于患者恢复,降低了患者住院期间的感染风险,自体血回输值得推广。 OBJECTIVE To compare the effect and infection of using autologous blood transfusion and homologous blood transfusion after surgery for ruptured tubal pregnancy.METHODS The effect and infection between 31 cases of homologous blood transfusion and 38 cases of autologous blood transfusion after ruptured tubal pregnancy surgery were compared.RESULTS C-reactive protein(CRP),neutrophils and hemoglobin were not significantly different(P0.05) in two groups.CRP in two groups 1h after transfusion and 1 d,2 d after surgery was significantly higher than that before transfusion(2.64±1.08 mg/L vs.15.50±5.60mg/L,P0.05;2.64±1.08 mg/L vs.93.80±16.40 mg/L,P0.05,2.64±1.08 mg/L vs.84.90±26.40mg/L,P0.05;3.00±1.05 mg/L vs.12.50±2.406mg/L,P0.05;3.00±1.05 mg/L vs.84.60±21.20 mg/L,P0.05;3.00士1.05 mg/L vs.70.10±30.40 mg/L).Compared with that at postoperative 1 d,CRP in homologous blood transfusion group 2 d after surgery decreased but had not significant difference.While compared with that at postoperative 1 d,CRP in autologous blood transfusion group 2 d after surgery was significantly lower(P0.05).Compared with homologous blood transfusion group,CRP in the autologous blood transfusion group at postoperative transfusion 1 h,1 d and 2 d were lower(P0.05).Neutrophils in two groups after transfusion 1 h,after surgery 1d,2d was significantly higher than that before transfusion(P0.05).Compared with that at postoperative 1 d,neutrophilsin homologous blood transfusion group 2 d after surgery decreased evidently but had no significant difference(P0.05).While compared with that in homologous blood transfusion group at postoperative 1 d,neutrophils in autologous blood transfusion group 2 d after surgery was significantly lower(P0.05).Compared with that in homologous blood transfusion group,neutrophils in the autologous blood transfusion group at postoperative transfusion 1 h and after surgery 1 d and 2 d were lower(P0.05).Hemoglobin in two groups 1 h after transfusion and 1 d after surgery was significantly lower than that before transfusion(P0.05) Compared with that at postoperative 1 d,hemoglobin in homologous blood transfusion group 2 d after surgery had no significant difference(P0.05).While compared with that at postoperative 1 d,hemoglobin in autologous blood transfusion group 2 d after surgery was significantly higher(P0.05),but had no significant difference compared with that before transfusion(P0.05). CONCLUSION Autologous blood transfusion helps patients recover faster and reduces the risk of infection during hospitalization.Autologous blood transfusion should be widely used in clinic.
出处 《中华医院感染学杂志》 CAS CSCD 北大核心 2012年第6期1195-1197,共3页 Chinese Journal of Nosocomiology
关键词 输卵管妊娠破裂 自体血回输 血库血输入 Ruptured tubal pregnancy Autologous blood transfusion Homologous blood transfusion
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