摘要
背景:人工生物材料在骨损伤康复过程运用中逐步成熟与多样化,为人体严重的髋关节损伤治疗提供了条件和研究方向。目的:对髋关节损伤后人工生物材料干预治疗的相关措施和移植后炎症反应的因素进行分类与综述。方法:应用计算机检索PubMed、维普和万方数据库中1990-01/2011-10关于髋关节损伤治疗及其人工材料修复方面的文章,在标题和摘要中以"髋关节,移植,生物材料,治疗"或"hip,transplantation,biological materials,treatment"为检索词进行检索。结果与结论:目前严重的髋关节损伤治疗技术大多以假体置换为主,从原始的股骨头置换发展到现在的全髋置换、半髋置换、表面髋置换及无柄髋置换等各类人工髋关节置换,技术现已日趋成熟,而移植的材料学特征和并发症是制约手术效果的重要因素。所以,尽量做到生物相容性好、使用寿命长、手术创伤更小和手术后并发症少的相关髋关节置换的研究,应是今后材料学和置换技术研究的方向。
BACKGROUND： Artificial biomaterials are gradually mature and diversified in bone injury rehabilitation process, providing the conditions and research direction for treatment of severe hip injuries in the human body. OBJECTIVE： To classify and review the measures about artificial biomaterial intervention for hip injuries and post-transplantation inflammatory factors. METHODS： A computer-based search of PubMed, VIP and Wanfang databases （1990-01/2011-10） were performed for articles about hip injuries and biomaterial repair using the keywords of ＂hip, transplantation, biological materials, treatment＂ in English and Chinese. RESULTS AND CONCLUSION： At present, prosthetic replacement is the main technique for treatment of severe hip injuries and it is going to maturation that is developed from femoral head replacement to total hip replacement, hemi-hip replacement, surface hip replacement and even stemless hip replacement. However, implant material characteristics and postoperative complications are the important factors to constraint the surgical results. Therefore, studies addressing how to improve biocompatibility, increase service life, lessen surgical trauma and decrease postoperative complications in hip replacement are the hotspots of the materials and replacement techniques in the future.
出处
《中国组织工程研究》
CAS
CSCD
2012年第8期1475-1478,共4页
Chinese Journal of Tissue Engineering Research
