摘要
目的观察臭氧联合胶原酶注射治疗脱出型腰椎间盘突出症的疗效。方法臭氧盘内消融术、胶原酶盘外溶解术联合应用治疗脱出型腰椎间盘突出症。结果治疗脱出型腰椎间盘突出症41例,共治疗50个椎间盘,采用Macnab疗效评价标准评价,优良率85.3%,术后12个月影像复查(CT、MRI)与术前对照显示AB值、R值术后是术前的36%、43%,有较为明显的缩小。结论本项技术治疗脱出型腰椎间盘突出症疗效肯定,胶原酶对纤维环有溶解作用,臭氧对髓核有氧化作用,两者结合疗效肯定,且随时间延长逐渐向好,术后1年影像检查明显变小。
Objective To assess the therapeutic effect of combination use of ozone and collagenase for the treatment of prolapsed lumbar intervertebral disc herniation. Methods Combination use of ozone intra-disc ablation and collagenase extra-disc dissolution was employed to treat acute lumbar intervertebral disc protrusion. A total of 41 patients （50 diseased intervertebral discs） were enrolled in this study. The clinical results were analyzed and the therapeutic efficacy was evaluated. Results Combination use of ozone ablation together with collagenase dissolution was carried out in 41 patients. According to Macnab criterion, the therapeutic efficacy was evaluated. The excellent effectiveness was achieved in 85.3% of patients. Follow- up CT scanning and MRI were performed 12 months after the treatment. Both preoperative and postoperative AB value and R value were determined and compared with each other. The postoperative AB value and R value were 36% and 43% of the preoperative ones, respectively. The reduction was very obvious. Conclusion The combination use of ozone and collagenase has reliable effectiveness in the treatment of prolapsed lumbar intervertebral disc herniation. Collagenase has proteolytic effect on the fiber ring, while ozone possesses oxidation effect on the nucleus pulposus. A combination use of the two has definite curative effect.
出处
《介入放射学杂志》
CSCD
北大核心
2012年第3期246-248,共3页
Journal of Interventional Radiology
关键词
臭氧
胶原酶
脱出型腰椎间盘突出症
疗效
ozone
collagenase
prolapsed lumbar intervertebral disc herniation
curative effect
