摘要
目的探讨益生菌药物对自发性腹膜炎(SBP)再发的预防效果。方法 51例肝硬化并SBP治疗后,在综合护肝治疗的基础上随机分为3组:A组18例,除外综合治疗外无其他用药;B组20例,予益生菌口服;C组13例,予喹诺酮类药物口服。观察其自发性腹膜炎再发生率。结果 A组与B组比较,SBP再发生率高(χ2=3.99,P<0.05)。A组与B、C组比较,SBP再发生率高,差异有统计学意义(χ2=5.26,P<0.05)。B组与C组比较,χ2=0.001,P>0.05,两治疗组间差异无统计学意义。结论益生菌对预防自发性腹膜炎再发有效。
Objective To investigate the prophylactic effect of probiotics to prevent the recurrence of spontaneous bacterial peritonitis （SBP）. Method 51 patients with liver cirrhosis complicated with SBP were randomly divided into 3 groups after treated with hepatoprotection ： Group A as the control group （n = 18 ） ; Group B treated with probiotics （n = 20） and Group C treated with Quinolones （ n = 13 ）. Result The recurrence rate of Group B （44.44%） was significantly lower than that of Group A （ 15% ） （X2 = 3.99, P 〈0. 05 ）. The recurrence rate of both Group B and C was significantly lower than that of Group A （X2 = 5.26, P 〈 0.05 ）. There was no significant difference between Groups B and C （X2 = 0. 001, P 〉 0.05 ）. Conclusion Probiotics can prevent the recurrence of spontaneous bacterial peritonitis effectively.
出处
《中国微生态学杂志》
CAS
CSCD
2012年第3期265-266,共2页
Chinese Journal of Microecology
关键词
益生菌
预防
自发性腹膜炎
再发
Probiotics
Prevention
Recurrence
Spontaneous bacterial peritonitis
