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奥曲肽治疗肝硬化上消化道出血的临床研究 被引量:16

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摘要 目的:探讨奥曲肽在治疗肝硬化并发上消化道出血中的临床疗效。方法:选择笔者所在医院肝硬化并发上消化道出血患者116例,随机分为治疗组58例和对照组58例。治疗组首次应用奥曲肽0.1mg加入小壶点滴后,于5%葡萄糖注射液500ml中加入奥曲肽0.5mg,以每小时25~50μg(每分钟10~15滴)的速度,持续静脉点滴,病情稳定后减量维持48h。对照组给予5%葡萄糖注射液500ml中加入垂体后叶素100U,以每分钟0.2U(每分钟15~20滴)的速度,持续静脉滴注24~72h,视治疗反应,逐渐加量至0.4U,同时,舌下含服硝酸甘油0.6mg,每30分钟1次。病情稳定后减量维持48h。两组均建立二条静脉通道,另一条给予抑酸、止血、补液,预防肝性脑病、预防感染、对症等综合治疗。结果:治疗组总有效率明显高于对照组,差异有统计学意义(P<0.05)。结论:奥曲肽对肝硬化上消化道出血疗效显著。
出处 《中外医学研究》 2012年第9期27-28,共2页 CHINESE AND FOREIGN MEDICAL RESEARCH
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