摘要
目的 了解腭骨外侧缝牵张的缝组织反应和组织再生机理。方法 采用NiTi SMA缝牵张器牵张幼犬双侧腭骨外侧缝 ,四环素荧光标记和组织学观察缝牵张 3 ,7,14 ,2 8,5 6d连续组织变化过程。结果 缝牵张初期骨缘外侧出现囊状分离带 ,此后成骨和成纤维细胞大量增殖 ,成骨活动沿囊性分隔和周边进行 ,直至新的骨缘形成 ,缝恢复正常形态。结论 缝成骨主要发生在骨缘与缝结缔组织交界处 ,骨组织再生极具空间效率 ,中央带纤维排列方式和修复可能具有屏障作用 ,阻止了跨缝骨性融合。
Objective The purpose of this study was to know the process of tissue response and regeneration in the palato maxillary suture under tensile forces.Methods Sutural tissue changes after 3,7,14,28,56 days of suture expansion were examined histologically and fluorescently.Results It was found that a cyst like zone appeared in the conjuncture of bony front and sutural connective tissue at the earyly stage of sutural expansion.Then a great amount of osteoblasts and fibroblasts proliferated.New bone deposited along the septum and the front of the cyst until the new bone front formed and the suture restored its original morphology.Conclusions The findings suggested that sutural expansion be a process of bone tissue regeneration and fibrous tissue repair.
出处
《中华整形外科杂志》
CAS
CSCD
北大核心
2000年第1期43-45,共3页
Chinese Journal of Plastic Surgery
关键词
缝牵张
腭裂
组织再生
修复
Suture expansion osteogenesis
Tissue regeneration
Cleft palate repair
