摘要
应用马来丝虫成虫抗原、鼠抗人 IgG_4单克隆抗体和碱性磷酸酶标记的羊抗鼠 IgG_4结合物做ELISA,对69份班氏丝虫微丝蚴血症者血清测定 IgG_4抗体。在血清稀释度1:100时阳性率高达97.10%。表明丝虫感染者血清 IgG_4水平明显升高。在治愈10余年的以往微丝坳血症者、原丝虫病流行区人群以及丝虫病基本消灭后10年内出生的儿童中,阳性率分别为18.03%,16.67%和17.65%。而在非丝虫病流行区仅有3.66%的人群出现阳性反应。
In the examination of IgG_4 antibodies of 69 bancroftian microfilaremic cases by ELISA,the positive rate was as high as 97.10%at1:100 dilution,Showing a prominent elevation of IgG4 antibodies in filarial infection.Among other groups examined,the positive rates were 18.03%,16.67% ard 17.65%,respectively,for previous mierofilare- mic cases which had been clearance of microfilariae for 10 years after treatment with DEC,population from erstwhile endemic areas and ehildren born within 10 years after the control of the disease.Only 3.66% of the people from non-endemic areas showed positive reaction.
出处
《中国寄生虫病防治杂志》
CSCD
1990年第3期214-215,共2页
Chinese Journal of Parasitic Disease Control
基金
本项目接受 UNDP/World Bank/WHO 热带病培训与研究特别规划处资助
