摘要
目的观察饮食控制基础上,多烯磷脂酰胆碱联合还原型谷胱甘肽治疗非酒精性脂肪性肝炎(NASH)的临床疗效。方法将87例非酒精性脂肪性肝炎患者随机分为2组。对照组给予饮食控制,同时口服易善复,疗程为12周;治疗组在对照组的基础上加用还原型谷胱甘肽静脉滴注,疗程为4周,再继续口服易善复8周。结果治疗组总有效率为81.82%,对照组总有效率为67.44%。治疗组总有效率明显高于对照组(P<0.05)。结论饮食控制基础上,多烯磷脂酰胆碱联合还原型谷胱甘肽治疗NASH具有较好的临床疗效,能有效改善NASH患者的体重指数、肝功能、血脂及肝脏影像学变化。
Objective To investgate the effect,polyene phosphatidylcholine combined With reduced glutathione in treatment of non-alcoholic steatohepatitis（NASH）.Methods 87 nonalcoholic steatohepatitis patients were divided into 2 groups randomly.Control group：diet control combining with ESSENTIALE 12 weeks;Treatment group：besides above treatment,intravenous drip reduced glutathione was added for 4 weeks,continuetaking ESSENTIALE 8 weeks.Results The general effective rate in treatment group（81.82%） was markedly higher than in control group（67.44%）.Conclusion Diet control basia,polyene phosphatidylcholine combined with reduced glutathione was safe and highly effective in the treatment of NASH.And can effectively improve the NASH Patients with BMI,liver function,serum lipids and liver imaging changes.
出处
《当代医学》
2012年第9期19-20,共2页
Contemporary Medicine
