摘要
目的探讨宫颈微偏腺癌(minimal deviation adenocarcinoma,MDA)的临床病理特征、诊断及鉴别诊断。方法3例宫颈微偏腺癌进行临床病理回顾性研究及相关文献复习。结果患者临床上多以水样白带、不规则阴道出血等为主要症状,宫颈肥大呈桶状和/或糜烂,镜下见增生的腺体形态不规则,扭曲呈鸡爪样或角状外翻,向宫颈壁深层浸润。结论宫颈微偏腺癌少见,早期确诊率低,易误诊。免疫化检测有助于该病的诊断与鉴别诊断。
Objective To investigate the clinical pathological characteristics and differential diagnosis of minimal deviation adenocareinoma （MDA）. Methods The data of three cases with diagnosis of MDA were analyzed vetrospectively and some literatures reviewed here. Results The important clinical symptoms were watery leueorrhea or vaginal bleeding irregularly. Most patients had the signs of cervical hypertrophy and/or erosion. Histology showed irregular glandular patterns,atypia was not obvious. The glands were characterized by irregular shapes,wisted feeling like chicken elawl. The tumors typically ex- hibited deep invasion of the cervical wall. Conclusion The minimal deviation adenocarcinoma of the uterine cervix is rare and prone to be misdiagnosed and miss-diagnosed. The investingations of pathomophology and IHC results which CEA, p53 and Ki67 are highly expressed. They are significant for MDA＇s diagnosis and differential diagnosis.
出处
《中国现代医生》
2012年第10期86-87,F0003,共3页
China Modern Doctor
关键词
宫颈
微偏腺癌
临床病理
诊断
Cervix
Minimal deviation adenoearcinoma（MDA）
Pathologic
Diagnosis
