摘要
目的:探讨帕利哌酮联合丙戊酸钠治疗脑外伤所致精神障碍攻击行为的疗效和药物副作用。方法:将80例有攻击行为的脑外伤所致精神障碍住院患者随机分为研究组(帕利哌酮联合丙戊酸钠治疗)40例、对照组(单用帕利哌酮治疗)40例,疗程4周。两组于治疗前及治疗第1、2、4周末采用外显攻击行为量表(MOAS)、治疗中出现的症状量表(TESS)评定疗效与不良反应。结果:两组治疗前后外显攻击行为量表评分差异有显著性(P<0.01)。治疗第2、4周末两组间比较差异有显著性(P<0.01)。结论:帕利哌酮联合丙戊酸钠治疗脑外伤所致精神障碍的攻击行为起效快,疗效更好且安全。
Objective ： To investigate the combined ketone piperazine PaUey valproate treatment of braintrauma induced mental disorders and aggressive behavior of the efficacy of medication side effects. Methods： 80 patients with aggressive behavior of hospitalized mental disorders due to traumatic brain injury were randomly divided into study group （Palley co- ketone piperazine sodium valproate treatment） 40 patients in the control group （piperazine- one therapy alone Paley） 40 cases course of 4 weeks. Two groups before treatment and treatment in the first explicit use of 1,2, 4 weekend attacks Scale （MOAS）, the treatment of symptoms scale （TESS） assessed the emcacy and adverse reactions. Results： There were explicit aggressive behavior before and after treatment scale score difference was statistically significant （P 〈 0.01 ）. 2,4 week of treatment, the difference between the two groups was significant （P 〈 0.01 ）. Conclusion： Palley piperazine ketone sodium valproate therapy combined mental disorders due to brain trauma rapid onset of aggressive behavior, and batter efficacy and safety.
出处
《内蒙古中医药》
2012年第3期1-2,共2页
Inner Mongolia Journal of Traditional Chinese Medicine
关键词
帕利哌酮
丙戊酸钠
脑外伤所致精神障碍
攻击行为
Palley piperazine ketone
sodium valproate
brain trauma induced mental disorders
attacks
