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2型糖尿病患者血尿酸水平与非酒精性脂肪肝的相关性研究 被引量:26

Relationship between serum uric acid and nonalcoholic fatty liver in patients with type 2 diabetes
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摘要 回顾性分析1007例住院2型糖尿病患者,分为伴和不伴非酒精性脂肪肝(NAFLD)2组,收集患者临床及生化资料。结果表明,血尿酸与血糖呈负相关,与体重指数及肾功能呈正相关(P〈0.01),伴NAFLD组年龄较低、2型糖尿病病程均短,血清尿酸升高,尿酸清除率降低;随血尿酸水平升高,发生NAFLD的风险增大。 A total of 1 007 inpatients with type 2 diabetes mellitus (T2DM) were divided into 2 groups, according to whether there was accompanied with nonalcoholic fatty liver(NAFLD) ; and the data of the two groups were analysed. Serum uric acid levels were positively correlated with body mass index and blood urea nitrogen and creatinine, while negatively correlated with HbAlc. T2DM patients complicated with NAFLD were younger, had shorter duration of T2DM, and showed impaired uric acid clearance with raised serum uric acid. The prevalence of NAFLD was higher with increasing serum uric acid levels.
出处 《中华内分泌代谢杂志》 CAS CSCD 北大核心 2012年第3期215-216,共2页 Chinese Journal of Endocrinology and Metabolism
关键词 非酒精性脂肪肝 糖尿病 2型 血清尿酸 Nonalcoholic fatty liver Diabetes mellitus, type 2 Serum uric acid
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