摘要
甲状腺疾病时机体常伴有血脂异常，以往认为甲状腺功能减退患者血胆固醇水平升高的主要机制是由甲状腺激素（TH）水平降低造成的。然而，临床上出现的一些特点往往无法用这种传统理论去解释。例如亚临床甲状腺功能减退时，促甲状腺素水平升高，TH水平正常，但血清总胆固醇（TC）水平升高。从以上现象可以看到在甲状腺功能减退时血清TC的变化除与TH有关外，也可能与TSH有某种尚未被人们认识的关系。本文拟综述有关TSH和胆固醇的最近研究进展。
Thyroid diseases are often accompanied with dyslipidemia. In the past, low level of thyroid hormone （TH） was considered a main factor in causing elevated level of blood cholesterol in hypothyroid patients. However, some clinical features can not be explained by this traditional theory. For example, in subclinical hypothyroid cases, both levels of thyroid-stimulating hormone （ TSH ） and serum total cholesterol（ TC ） increase, while TH level remains normal. From this phenomenon, we speculate that in case with hypothyroidism, not only there is a relationship between serum TC and TH levels, but also serum TC level change is related to TSH in some way, which has not been noticed. The purpose of this paper is to review the new and most advanced progress in the research of TSH and cholesterol.
出处
《中华内分泌代谢杂志》
CAS
CSCD
北大核心
2012年第3期175-177,共3页
Chinese Journal of Endocrinology and Metabolism
基金
国家自然科学基金资助项目（30971409）
