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自噬与软骨及其损伤相关性 被引量:5

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摘要 自噬是存在于真核细胞,与细胞生长、增殖、凋亡发生过程相关的普遍而特有的生命现象。自噬可能是正常软骨细胞的一种保护或平衡机制,自噬妥协、细胞凋亡活跃、骨关节炎形成和发展三者之间密切相关。全面认识自噬在软骨细胞中的分子基础和调控机制,对各种原因引起的软骨损伤、退变的治疗具有重要意义。该文就细胞自噬与软骨及其损伤相关性研究作一综述。
出处 《国际骨科学杂志》 2012年第2期96-98,共3页 International Journal of Orthopaedics
基金 国家自然科学基金(30973025) 安徽省教育厅自然科学研究基金重点项目(KJ2010A320)
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