摘要
目的评价覆膜支架治疗恶性食管-气管瘘临床疗效。方法 32例因食管癌或支气管癌引起食管-气管瘘行食管或气管内覆膜支架置入治疗,记录技术成功率、首次临床成功率及失败率、瘘口重新开放率以及各种并发症。采用Kaplan-Meier方法计算首次临床成功患者及首次临床失败患者生存时间,用log-rank检验两组患者有无差异。结果 32例患者支架置入全部成功,技术成功率为100%,28例瘘口封堵满意,首次临床成功率88%,4例瘘口未能完全封堵,首次临床失败率12%,28例瘘口封堵满意患者中,6例随访中出现瘘口复发,再次介入治疗后瘘口封闭。所有患者均已死亡,平均生存期10.4月。首次瘘口完全封堵患者平均生存期11.3月,首次瘘口未完全封堵患者平均生存期4.2月,P<0.001。结论恶性食管-气管瘘患者应用覆膜支架治疗有效,部分瘘口完全封闭后可再复发,再复发患者可继续行支架置入治疗。
Objective To evaluate long-term clinical results of palliative treatment of esophagoresporatory fistulas（ERFs） with covered expandable metallic stents. Methods Thirty-two patients with ERFs due to esophageal or bronchogenic carcinoma were treated with covered expandable esophageal or tracheobronehial metallic stents. Results Stetu placement was technically successful in all patients. The stent completely sealed off the fistula in 28（88%） of 32 patients so that they had no further aspiration symptoms （initial clinical success）. Four （12%） of 32 patients had persistent aspiration symptoms due to incomplete ERF closure （initial clinical failure）. Mean survival in patients with initial clinical success was significantly longer than that in patients with initial clinical failure （11.3 vs 4.2 months, P〈0.01）. Conclusion The use of covered expandable metallic stetus appears to be safe and feasible for the palliative treatment of malignant esophagoresporatory fistulas.
出处
《当代医学》
2012年第6期83-85,共3页
Contemporary Medicine
关键词
食管-气管瘘
覆膜支架
介入治疗
疗效
Esophagoresporatory fistula
Covered expandable metallic stetus
Inteventional trealanent
Efficacy
