摘要
目的探讨气管内支架置入联合动脉灌注化疗治疗恶性中心性气道狭窄的临床疗效。方法 15例恶性肿瘤压迫或侵犯引起气管狭窄和严重的呼吸困难患者,在DSA透视下分别置入镍钛合金自膨式气管支架,7～10d呼吸困难改善后进行了后续的动脉灌注化疗。结果 15例患者一次性成功置入气管支架15个,术后患者气促症状明显缓解,经动脉化疗灌注后CR3例(20%),PR7例(46.7%),总有效率66.7%,平均生存8.3个月。结论恶性中心性气道狭窄的患者,支架置入能有效缓解临床症状,提高患者生存质量,结合后续的动脉灌注化疗能延长患者的生存时间。
Objective To observe the curative effect of metallic stents implantation combined with intraarterial infusion chemotherapy in treatment of malignant airway obstruction.Methods Fifteen patients with airway obstruction and dyspnea caused by malignant carcinoma underwent self-expanding Ni-Ti alloy stents placement under fluoroscopy in the DSA,then additional intraarterial infusion chemotherapy 7～10days later.Results The placement of metallic stents was successful in one time.Shortness of breath was relieved obviously.After chemotherapy,there were 3 cases of CR,14 cases of PR,the total effective rate reached 66.7%.Conclusion Metallic stents are useful for relieving respiratory distress and improving life quality in patients with malignant airway obstruction,additional intraarterial infusion chemotherapy can increase the survival time of the patients.
出处
《当代医学》
2012年第6期78-80,共3页
Contemporary Medicine
关键词
气管狭窄
恶性
肿瘤
内支架
介入治疗
Tracheal stenosis
malignant carcinoma
stent
interventional therapy
