摘要
目的利用宝石CT能谱成像技术测量正常甲状腺含碘量，计算甲状腺与胸锁乳突肌含碘量的碘比值，为高碘或缺碘性甲状腺疾病诊断提供参考依据。方法采用美国GE公司生产的宝石CT,对来自潍坊医学院的226例怀疑颈部或颈椎疾病患者进行能谱扫描，扫描范围包括甲状腺，胸锁乳突肌。其中男119例，女107例，年龄18～77岁，平均年龄（464-17）岁。将扫描数据传至AW4．4工作站，利用GSIViewer软件处理，找出甲状腺与胸锁乳突肌的最佳对比噪声比及其所对应的单能量图像，在碘基图像上测量甲状腺左右叶、两侧胸锁乳突肌含碘量，计算二者含碘量比值。结果甲状腺左右叶总含碘量为（1．5233±0．4318）mg／（3133．。，其中左叶为（1．52304-0．4271）mg／cm^3.，右叶为（1．5236．4±0．4365）mg／cm^3，二者比较差异无统计学意义（f=0．0084，P〉0．05）。男性甲状腺含碘量为（1．63954±0．4105）mg／em^3，女性为（1．42384±0．3832）mg／cm^3，二者比较差异有统计学意义（t=3．4743，P〈0．01）。甲状腺与胸锁乳突肌含碘量的碘比值为96．62714-33．2442，其中男性比值为94．62504-37．3621，女性比值为98．00004±29．0737，二者比较差异无统计学意义（t=0．3817，P〉0．05）。随年龄增长甲状腺含碘量呈逐渐下降趋势，组间比较差异有统计学意义（F=9．66，P〈0．01）；其中〈40岁组[（1．72564±0．4631）mg／cm^3]甲状腺含碘量高于40—60岁组[（1．45174±0．3643）mg／cm。]和〉60岁组[（1．43684±0．3465）mg／cm^3，q值分别为5．6195、5．4158，P均〈0．01]。结论宝石CT能谱成像能测定甲状腺含碘量，反映人体碘水平，对高碘或缺碘性甲状腺疾病诊断有重要指导意义。
Objective To measure the iodine content of normal thyroid and the sternocleidomastoid muscle with gemstone spectral imaging （GSI）, in order to offer diagnostic reference for iodine excess or iodine deficiency disorders. Methods A total of 226 cases of patients with suspected neck or cervical disease underwent GSI of the neck, the thyroid and the sternocleidomastoid muscle. One hundred and nineteen cases were male and 107 female, aged 18 to 77 years, average age（46 ＋ 17） years. Data were transmitted to AW 4.4 workstation and processed using GSI Viewer software to obtain the best contrast-to-noise ratio（CNR） of thyroid to sternoeleidomastoid muscle and corresponding singe-energy images. Iodine content of left and right thyroid lobes and both sides of sternocleidomastoid muscle as well as iodine content ratio of thyroid to sternocleidomastoid muscle were calculated in the iodine-based images. Results Total iodine content of the left and the right lobes of the thyroid was （1.5233 ± 0.4318）mg/cm3, of the left lobe was （1.5230 ± 0.4271 ）mg/cm3, of the right lobe was （1.5236 ±0.4365）mg/em3, there was no significant difference statistically between the two（t = 0.0084, P 〉 0.05）. The iodine content of the male was （1.6395 ±0.4105）mg/cm3, and of the female was （1.4238 ± 0.3832）mg/em3, there was statistically asignificant difference between the two（t = 3.4743, P 〈 0.01 ）. Iodine content ratio of thyroid to sternocleidomastoid muscle was 96.6271 ± 33.2442, the ratio in male was 94.6250 ±37.3621 and in female was 98.0000± 29.0737, there was no statistical difference between the two（t = 0.3817, P 〉 0.05 ）. The iodine content of thyroid decreased gradually with age, the difference between groups was statistically significant（F = 9.66, P 〈 0.01 ）. The iodine content in 〈 40 age group[ （1.7256 ± 0.4631 ）mg/em3] was higher than that in 40 - 60 age group[ （1.4517 ± 0.3643）mg/cm3] and 〉 60 age group [ （1.4368 ± 0.3465）mg/cm3; q = 5.6195, 5.4158, all P 〈 0.01）. Conclusions It is easy to calculate thyroid iodine content with gemstone spectral imaging, which can reflect the iodine level of our body, and is helpful for the diagnosis of iodine excess or iodine deficiency disorders.
出处
《中国地方病学杂志》
CAS
CSCD
北大核心
2012年第2期212-215,共4页
Chinese Jouranl of Endemiology
关键词
体层摄影术
X线计算机
能谱成像
甲状腺
碘
Tomoraphy, X-ray computed
Gemstone spectral imaging
Thyroid gland
Iodine
