摘要
目的探讨该院近3年血培养中阳性标本的病原菌分布及药敏情况,为临床抗感染治疗提供依据。方法对近3年送到检验科的血培养标本进行回顾性分析。结果共检出阳性血培养标本5 921例,检出的病原菌中肠杆科细菌占36.83%(2 181/5 921),非发酵菌30.67%(1 816/5 921),葡萄球菌属10.55%(625/5 921),肠球菌属9.30%(551/5 921),真菌6.92%(410/5 921),污染菌6.08%(280/5 921),布氏杆菌0.98%(58/5 921)。结论血培养中葡萄球菌是极为重要的致病菌,但革兰阴性菌所引起的感染也不容忽视。抗菌药物耐药率高,且具有高耐药与多重耐药的特点,治疗需以药物监测为依据。了解血液感染细菌的分布特征和耐药性,对减少院内感染,指导临床合理使用抗菌药物有重要意义。
Objective To explore the distribution and the drug resistance of pathogens from blood cultures,and to provide evidences for clinical anti-infection treatment.Methods The pathogens and drug susceptibilities of 5 921 blood samples were collected from the hospital in the past three years.Results In 5 921 positive strains,pathogen of intestinal stem secco bacteria was 36.83%（2 181/5 921）,vibrionaceae was 30.67%（1 816/5 921）,staph was 10.55%（625/5 921）,the bowel coccus was 9.30%（551/5 921）,fungi was 6.92%（410/5 921）,bacteria pollution was（6.08%）,brinell coli was 0.98%（58/5 921）.Conclusion The infections caused by Gram-negative bacilli should not be neglected although staphylococci is the major pathogen in the blood culture.The antibiotics resistant rate of all bacteria rise is gradually increasing,moreover,antibiotic therapy should be taken and monitored according to the detected results.
出处
《检验医学与临床》
CAS
2012年第6期676-677,679,共3页
Laboratory Medicine and Clinic
关键词
血培养
耐药性
细菌培养
凝固酶阴性葡萄球菌
blood culture
drug-resistance
bacterial culture
coagulase negative staphylococcus
