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非小细胞肺癌140例术前辅助化疗临床分析 被引量:2

AN ANALYSIS OF PREOPERATIVE CHEMOTHERAPY FOR 140 PATIENTS WITH NON - SMALL CELL LUNG CANCER
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摘要 目的探讨辅助化疗对非小细胞肺癌外科手术治疗的应用价值。方法选择2002年7月—2005年7月非小细胞肺癌患者273例,随机分为2组,试验组手术治疗前给予吉西他滨+顺铂化疗方案治疗3个周期,停药3~4周后施行手术。对照组采用单纯手术治疗。结果试验组术后3、5年生存率均高于对照组(P<0.05)。结论术前辅助化疗安全有效,能提高非小细胞肺癌患者手术后生存率。 Objective To investigate the application of adjuvant chemotherapy for non - small cell lung cancer surgical treatment. Methods Two hundred and seventy - three patients with non - small cell lung cancer between July 2002 to July 2005 were selected. The patients were randomly divided into two groups, treatment group and control group. Treatment group received 3 cycles of chemotherapy before the operation for followed by the surgery after 3 to 4 weeks. Control group underwent the operation without chemotherapy. Results The survival rates of 3 or 5 - year in the treatment group were higher than control group (P 〈 0.05 ). Conclusion Preoperative chemotherapy is safe and effective and it can improve the survival rate of patients with non - small cell lung cancer after surgery.
出处 《河北医科大学学报》 CAS 2012年第1期28-30,共3页 Journal of Hebei Medical University
关键词 非小细胞肺 抗肿瘤联合化疗方案 治疗结果 carcinoma, non - small cell lung antineoplastic combined chzmotherapy protocols treatment outcome
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  • 1GERGOULIAS V,ANDROULAKIS N,LOTSUKIS A,et al.Third-goneration chemotheraph agents in the treatment of advanced non-small cell lung cancer:ameta-analysis[J].J Thoral Oncol,2007,2(9):845-853.
  • 2鲍军,蔡高翔,潘琦,薛洁皓,郭再君,蓝之源.术前新辅助化疗在局部晚期非小细胞肺癌治疗中的应用评价[J].皖南医学院学报,2008,27(3):191-193. 被引量:8
  • 3HOTTA K,KIURA K,FUJIWARA Y,et al.Role of survival post-progression in phase Ⅲ trials of systemic chemotherapy in advanced non-small-cell lung cancer:a systematic review[J].PLoS One,2011,6(11):2664-2666.
  • 4KATSURAGI N,SHIRAISHI Y,KITA H,et al.Locally advanced non-small cell lung cancer completely resected after induction therapy[J].Kyobu Geka,2008,61(1):9-14.
  • 5KUNITOH H,KATO H,TSUBOI M,et al.Phase Ⅱ trial of preoperative chemoradiotherapy followed by surgical resection in patients with superior sulcus non-small-cell lung cancers:report of Japan Clinical Oncology Group trial 9806[J].J Clin Oncol,2008,26(4):644-649.
  • 6王斌,唐超,王萍萍.术前化疗对Ⅲ期非小细胞肺癌患者生存的影响[J].基层医学论坛,2008,12(19):577-580. 被引量:3
  • 7DETTERBECK FC,SOCINSKI MA,GRALLA RJ,et al.Neoadjuvant chemotherapy with gemcitabine-containing regimens in patients with early-stage non-small cell lung cancer[J].J Thorac Oncol,2008,3(1):37-45.
  • 8QUOIX E.Optimal pharmacotherapeutic strategies for elderly patients with advanced non-small cell lung cancer[J].Drugs Aging,2011,28(11):885-894.
  • 9COLEMAN MH,BUENO R.Role of adjuvant chemotherapy in NSCLC (stages Ⅰ to Ⅲ)[J].Surg Oncol Clin N Am,2011,20(4):757-767.
  • 10DALY BD,CERFOLIO RJ,KRASNA MJ.Role of surgery following induction therapy for stage Ⅲ non-small cell lung cancer[J].Surg Oncol Clin N Am,2011,20(4):721-732.

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