期刊文献+

急性缺血性脑血管病合并脑微出血的临床分析 被引量:3

THE CLINICAL ANALYSIS OF ACUTE ISCHEMIC CEREBROVASCULAR DISEASE COMBINED WITH CEREBRAL MICROBLEEDS
暂未订购
导出
摘要 目的 探讨不同类型的急性缺血性脑血管病合并脑微出血(cerebral microbleeds,CMB)的阳性检出率及其临床意义.方法 将急性缺血性脑血管病患者204例以及同期健康体检者35例均行常规磁共振成像(magnetic resonance imaging,MRI)和磁共振梯度回波T2加权成像(T2*-weighted gradient-echo magnetic resonance imaging,GRE-T2*WI) 检查.结果 动脉粥样硬化血栓性脑梗死组、心源性脑栓塞组及腔隙性脑梗死组患者CMB阳性检出率均高于正常对照组,差异有统计学意义(P<0.05);短暂性缺血发作组与正常对照组的阳性检出率差异无统计学意义(P>0.05).结论 GRE-T2*WI对CMB敏感性较高,对急性缺血性脑血管病患者的治疗和预后具有指导意义. Objective To investigate the positive detection rate and clinical significance of different types of acute ischemic cerebrovascular disease combined with cerebral microbleeds (CMB). Methods A total of 204 patients with acute ischemic c'erebrovascular disease and 35 healthy control underwent examinations of magnetic resonance imaging ( MRI ) and T2 * - weighted gradient - echo magnetic resonance imaging (GRE - T2 * WI ). Results The CMB positive detection rate of the atherosclerosis thrombosis cerebral infarction group, the cardiogenic cerebral embolism group and the lacunar cerebral infarction group were higher than the control group, and there were statistical differences between these groups (P 〈 0.05 ). There was no significant difference between transient ischemic group (TIA) and control group in deteetion rate (P 〉 0.05 ). Conclusion GRE - T2 * WI has higher sensitivity to CMB, and it has a guiding role in the the therapy and the prognosis of patients with acute ischemie cerebrovascular disease.
作者 王洪敏
出处 《河北医科大学学报》 CAS 2012年第1期25-27,共3页 Journal of Hebei Medical University
关键词 脑血管障碍 脑出血 磁共振成像 弥散 cerebmvascular disorders cerebral hemorrhage diffusion magnetic resonance imaging
  • 相关文献

参考文献6

  • 1KAKUDA W,THIJS VN,LANSBERG MG,et al.Clinical importance of microbleeds in patients receiving Ⅳ thrombolysis[J].Neurology,2005,65(8):1175-1178.
  • 2LEE SH,BAE HJ,KWON SJ,et al.Cerebral microbleeds are regionally associated with intracerebral hemorrhage[J].Neurology,2004,62(1):72-76.
  • 3各类脑血管疾病诊断要点[J].中华神经科杂志,1996,29(6):379-380. 被引量:33100
  • 4NIGHOGHOSSIAN N,HERMIER M,ADELEINE P,et al.Old microbleeds are a potential risk factor for cerebral bleeding after ischemic stroke:a gradient-techo T2*-weighted brain MRI study[J].Stroke,2002,33(3):735-742.
  • 5WERRING DJ,COWARD LJ,LOSSEFF NA,et al.Cerebral microbleeds are common in ischemic stroke but rare in TIA[J].Neurology,2005,65(2):1914-1918.
  • 6TROUILLAS P,KUMMER VR.Classification and pathogenesis of cerebral hemorrhages after thrombolysis in ischemic stroke[J].Stroke,2006,37(2):556-561.

共引文献33099

同被引文献28

  • 1Nandigam R,Viswanathan A,Delgado P,et al.MR imaging detection of cerebral microbleeds:effect of susceptibility- weighted imaging,section thickness,and field strength[J].A- merican Journal of Neuroradiology ,2009,30(2):338-343.
  • 2Bokura H,Saika R,Yamaguchi T,et al.Microbleeds are asso- ciated with subsequent hemorrhagic and ischemic stroke in healthy elderly individuals[J],Stroke,2011,42(7):1 867-1871.
  • 3Poels M,lkram Van der Lugt A,et al.Cerebral microb- leeds are associated with worse cognitive function.The Rotter- dam Scan Study[J].Neurology,2012,78(5):326-333.
  • 4Arsava E,Rahman R,Rosand J,et al.Severity of leukoaraiosis correlates with clinical outcome after ischemic stroke[J].Neu- rology,2009,72(16):1403-1410.
  • 5Poels MM,Ikram MA,van der Lugt A,et al.Incidence of cerebral microbleeds in the general population the Rotterdam Scan Study[J].Stroke,2011,42(3):656-661.
  • 6Sueda Y, Naka H, Ohtsuki T. Positional relationship between recurrent intracerebral hemorrhage/lacunars infarction and previously detected microbleeds [J]. AJNR, 2010, 31 (8): 1498-1503.
  • 7Wu H, Jia Q, Liu G, et al. Decreased uric acid levels correlate with poor outcomes in acute ischemic stroke patients, but not in cerebral hemorrhage patients[J]. J Stroke Cerebrovasc Dis, 2014, 23(3): 469-475.
  • 8Zhao BQ, Ikoda Y, lhara H, et al. Essential role of endogenous tissue plasminogen activator through matrix metanoproteinase 9 induction and expression on heparin-produced cerebral hemorrhage after cerebral ischcmia in mice[J]. Blood, 2004, 103(7): 2610-2616.
  • 9李春霞,王翠艳,杜怡峰,刘兆孔.急性缺血性脑血管病中脑微出血的临床表现与磁共振梯度回波加权成像特点[J].中华老年心脑血管病杂志,2009,11(1):4-6. 被引量:3
  • 10周志明,杨松,岳炫烨,朱武生,马敏敏,徐格林,刘新峰.急性脑梗死患者脑微出血相关因素分析[J].中华医学杂志,2010,90(7):451-453. 被引量:52

引证文献3

二级引证文献28

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部