摘要
为观察皮疾散联合丁酸氢化可的松乳膏治疗肛心湿疹的疗效，本研究将95例慢性肛剧湿疹患者随机分为衍玎川（50例）和对照组（45例），对照组单纯用丁酸氢化可的松乳膏外涂治疗，治疗组存对照组治疗基础上加皮疾散外洗治疗，两组均以2周为一疗程。结果显示，治疗组痊愈36例（72．0％），有效12例，无效2例，总有效率为88．0％；对照组痊愈20例（11.4％），有效21例，无效4例，总有效率为75．6％。两组总有效率比较，差异无显著意义，P〉0．05；但治疗组痊愈率明显高于对照组，P〈0．05。停药8周后治疗组痊愈者复发率为44．4％（16／36），对照组为75．0％（15／20），刈照绀复发率明显高于治疗组，P〈0．05。结果表明，皮疾散联合丁酸氢化可的松乳膏治疗肛周湿疹疗效满患，且复发率低，值得临床推广。
The objective of this study was 1o observe the therapeutic effect of the combination therapy（self designed Piji San＋Butyric acid hydrocortisone emulsion ointment）in the treatment of perianal eczema. This study divided randomly the 95 patients with chronic perianal eczema into treatment group（ n=50） and control group （ n=45）. Treatment group received above combination therapy,while control group only bu tyric acid hydrocortisone emulsion ointment, the treatment course of both groups was all 2 weeks. As re suits,in treatment group36 cases （72.0%,36/50） were cured, 12 were effective,2 were of non response, total effective rate was 88.0% ,meanwhile in control group,20 cases（44.4% ,20/45）,21,4,75.6% ,rcspec tively;the total effective rate had no significant difference between both groups（ P〈0.05）,but curatiw＇ rate of treatment group was distinctly higher than that of control group（ P〈0. 05） ; later 8 weeks after withdrawal the recurrence rate of cured patients in treatment group was 4/1.4% （16/36）,while in control group,75.0% （15/20）,apparently,in control group was significantly higher than in control group（ P〈 0.05）. Results show that Piji San combined with butyric acid hydroeortisone emulsion ointrnenl in the treatment of perianal eczema has satisfactory therapeutic effect, lower recurrence rate, thus it is worlby to be popularized clinically.
出处
《中国肛肠病杂志》
2012年第2期60-61,共2页
Chinese Journal of Coloproctology
关键词
肛周湿疹
联合疗法
皮疾散
丁酸氢化可的松乳膏
疗效
Perianal eczema
Combination therapy
Piji San
Butyric acid hydrocortisone emulsion oinlment
Therapeutic effect
