摘要
为系统性评价中药和西药保留灌肠治疗溃疡性结肠炎（UC）的临床疗效，为中药保留灌肠治疗UC提供循证医学依据，本研究通过检索万方数据库，纳入2005年1月1日至今的关于中药和西药保留灌肠治疗UC的随机对照研究（RCT），采用RevMan4．2软件对文献的异质性进行检验，并分析痊愈率和总有效率。结果显示，共纳入5项RCT研究。中药和阿约保留灌肠的痊愈率分别为44．7％（110／246）和16．1％（37／230），差异具有统计学意义（Z=6．58，P〈0．00001）。中药和两药保留灌肠的总有效率分别为98．4％（242／246）和82．6％（190／230），差异具有统计学意义（Z=5．08，P〈o．00001）。结果表明，中药保留灌肠治疗UC的疗效优于西药保留灌肠。
The objective of this study was to systematicly evaluate the clinical therapeutic effect of Chinese materia medica and western drugs used in retention enema for treating ulcerative colitis（UC）,so as to pro vide the basis of evidence-based medicine for Chinese materia medica used in retention enema in the treat- ment of UC. Through retrieving Wanfang database this study involved the 5 items of RCTs（ from 2005-01- 01 to now） related to above-mentioned two enema therapies,adopted Rev man 4.2 software for examiningthe heterogenicity of the literature,and analysed curative rate and total effective rate. As resulls, the cura rive rate and total effective rate in Chinese materia medica and Western durgs was 44. 7%（110/246） vs 16.1%（37/230）,98.4%（242/246） vs 82.---6.58, P 〈0.00001, Z =5.08, P〈0.00001. western drugs in retention enema for UC. 6 % （ 190/230）, respectively, there all was significant difference（ Z O0001）,which show that Chinese materia medica is superior to
出处
《中国肛肠病杂志》
2012年第2期34-36,共3页
Chinese Journal of Coloproctology
关键词
溃疡性结肠炎
中药
西药
保留灌肠
系统评价
Ulcerative colitis
Traditional Chinese drug
Western drug
Retention enema
Systematic evaluation
