摘要
目的:观察舒血宁注射液(成分:银杏提取物)对脑梗塞患者血小板活化的影响。方法:将63例脑梗塞患者随机分为两组,其中拜阿司匹灵组(aspirin group)31例,单用拜阿司匹灵治疗,舒血宁注射液+拜阿司匹灵组(Gingko+aspirin group)32例,予拜阿司匹灵联合舒血宁注射液治疗,并设立健康对照组30名,测定两组脑梗塞患者急性期和恢复期及健康对照组的PAC1、CD62P表达率,所测结果进行比较。结果:两组脑梗塞经分别治疗后,舒血宁注射液+拜阿司匹灵组PAC1、CD62P表达率较拜阿司匹灵组降低,差异有统计学意义(P<0.01)。结论:舒血宁注射液联合拜阿司匹灵可更好的抑制血小板活化。
Objective： To investigate the effect of Shuxuening Injection（component：Gingko extraction）on cerebral infarction.Methods： 63 cases of cerebral infarction were randomly divided into two groups,They included 31 cases of bay aspirin group（aspirin group）,treated with bay aspirin;32 cases of Shuxuening Injection combination with bay aspirin group（Gingko＋aspirin group）,treated combination with Shuxuening Injection and bay aspirin;and 30 normal persons were served as healthy control group,determine the posi-tive rate of PAC1,CD62P on the acute stage and recovery stage in the two groups and healthy control group,and researchers were com-pared.Results： After treatment respectively,Expression of PAC1 and CD62P in the Shuxuening Injection combination with bay aspirin group were lower than those in bay aspirin group,suggesting the difference has statistically significant（P〈0.01）.Conclusions： Treatment by Shuxuening Injection combination with bay aspirin can inhibit the platelet activity better.
出处
《现代生物医学进展》
CAS
2012年第2期324-326,共3页
Progress in Modern Biomedicine
关键词
脑梗塞
血小板活化
舒血宁注射液
Cerebral infraction
Platelet activation
Shuxuening Injection
