摘要
目的:探讨3次/日注射诺和锐30强化和2次/日注射诺和灵30R治疗2型糖尿病的疗效及低血糖风险。方法:收治经口服降糖药治疗效果不佳的2型糖尿病患者56例,随机分为诺和锐30强化治疗组和诺和灵30R组各28例,随访3个月。观察两组治疗前后空腹血糖、餐后2小时血糖、HbA1c、血糖达标天数及低血糖发生率等。结果:两组比较诺和锐30强化治疗组达标时间更短(P<0.01),低血糖发生率更低(P<0.01)。结论:诺和锐30强化治疗降血糖快,低血糖发生率低,可作为治疗2型糖尿病的较理想的治疗方法之一。
Abstract Objective：To investigate the effica- cy and hypoglycemia risk of three times dai- ly injections of aspart 30 and twice daily in- jections of Novolin 30R in type 2 diabetes mellitus treatments. Methods： 56 patients with type 2 diabetes who were in Poor glyce- mic control with oral antidiabetic drug were randomly divided into the group of intensive therapy with aspart 30 and the group of Nov- olin 30R, which group was 28 cases. Total tbl]ow- up was three months. We observed the FBG, 2hPBG, HbAI c, time of reaching target of glucose and accidence of hypogly- cemia before and after treatments. Result： The group of intensive therapy with aspart 30 was with shorter time of reaching target of glucose（ P 〈 0.01 ） and lower accidence of hypoglycemia（ P 〈 0. 01 ） than the group of Novolin 30R. Conclusion： The intensive therapy with aspart 30,which has faster hy- poglycemic effect and lower accidence of hy- poglycemia, can be One of the preferred method in treating type 2 diabetes.
