摘要
目的:探讨瑞芬太尼-氯胺酮在小儿静脉麻醉中有效性和安全性。方法:将80例择期进行手术的患儿随机分为两组,观察组和对照组各40例。观察组采用瑞芬太尼复合氯胺酮静脉麻醉,对照组采用氯胺酮静脉麻醉。结果:观察组患儿术中心率明显低于对照组(P<0.05);观察组患儿氯胺酮总用量和苏醒时间明显少于对照组(P<0.05)。结论:瑞芬太尼复合氯胺酮静脉麻醉可大大减少氯胺酮的用量,缩短苏醒时间,无明显的心血管、肝肾功能损伤,安全性好。
Abstract Objective: To study the efficacy and safety of remifentanil - ketamineintrave- nousanesthesiainpediatric. Methods: 80cases included were randomly divided into two groups, 40 cases of observation groupand 40case of control group. Observationgroup were treated wlthintravenous anesthesiafor- remifentanilcornbined with ketamlne, and control group for ketamineintravenous anes- thesia. Results:The heart rateof observation groupwas significantly lower thanthe control group ( P 〈 0. 05 ) ; the total amount ofketami- neused in observation groupandrecovery time- of observation groupwere significantly less thancontrol group ( P 〈 0. 05 ). Conclusion: Remifentanilintravenousketamineanesthesia cangreatly reducethe amount ofketamine, shortening recovery time, with no significant- cardiovascular, liver and kidneydysfunctionis safe to use.
关键词
小儿麻醉
瑞芬太尼
氯胺酮
Pediatric Anesthesia
Remifen- tanil
Ketamine