摘要
目的：研究喹诺酮类抗菌药的用量与细菌耐药率之间的关系,促进临床合理用药。方法：回顾性调查武汉地区7家医院2005～2009年喹诺酮类抗菌药的用量,并与监测菌的耐药率做相关分析。结果：大多数监测菌种对喹诺酮类药的耐药率均超过30%;鲍曼不动杆菌对喹诺酮类药的耐药率随喹诺酮类药用量的变化而变化,与喹诺酮类药总用药频度高度相关。结论：喹诺酮类药对多数常见菌种的耐药率较高,其用药频度对细菌耐药性变异也有一定影响。应严格把握喹诺酮类药的临床适应证,加强对喹诺酮类药的管理,以减少或延缓细菌耐药性的发生。
CaCu3Ti4O12（CCTO） ceramic was prepared via solid state synthesis methods.The effects of sintering temperature on the crystalline phase,microstructure,density and dielectric properties of CCTO at C band（3.95 GHz～5.85 GHz） was studied.The results show that for the sample sintered at 1040 ℃,there are some un-reacted TiO2 existing,which disappear as the sintering temperature increases.The grain size of the sample sintered at 1080 ℃ is larger and more uniform than that sintered at 1040 ℃ and 1060 ℃.Obvious melting is observed in the sample sintered at 1100 ℃.The density of the samples increases as the sintering temperature increases,and reaches maximum at 1080℃.The dielectric constant and dielectric loss of all the samples change little as the frequency increasing.With the increase of sintering temperature from 1040℃ to 1080℃,the dielectric constant of the samples obviously increases,and then decreases when the sintering temperature increases from 1080 ℃ to 1100 ℃.The CCTO ceramics sintered at 1080 ℃ have the highest dielectric constant but the lowest dielectric loss.
出处
《热加工工艺》
CSCD
北大核心
2012年第6期7-9,共3页
Hot Working Technology
基金
国家自然科学基金资助项目（51072165）
凝固技术国家重点实验室自主研究课题资助项目（PK200901）
关键词
喹诺酮
用药频度
耐药
solid state synthesis methods CaCu3Ti4O12 ceramics dielectric properties
