摘要
目的探索低浓度（１．０４０ｍｇ／ｍ３）丙烯腈（Ａｃｒｙｌｏｎｉｔｒｉｌｅ，ＡＮ）对职业人群健康状况的影响。方法对２２４名ＡＮ作业工人（接触组）和２２４名不接触毒物工人（对照组）进行流行病学调查。结果①ＡＮ作业人群可有类神经症和咽部刺激等症状，其中头昏、记忆力减退、胸闷、食欲不振等比例较对照组高（Ｐ＜０．０５）。②血清 －ＧＴ、ＵＳＣ Ｎ平均水平比对照组高（Ｐ＜０．０５）。③接触组人群外周血淋巴细胞微核率较对照组明显升高，且吸烟与ＡＮ遗传效应之间有某种协同作用。结论认为 ＡＮ在低于国家最高容许浓度（２ ｍｇ／ｍ３）下，对接触人群仍会发生一定影响。
Objective To look for the health effects on workers exposed to concentration (1. 040 mg/m3) acrylonitrile (AN). Methods An epidemiologic study with 224 workers exposed to AN (subjects) and same number of non-exposed controls were carried out.Results The detecting rates of dizziness, hypomnesia, chest chokign and anorexia in the subjects were significantly higher than those in the controls (P < 0. 05). The levels of serum -GT and urine SCN, compared with that of controls, were significantly increased (P < 0. 05). The average rate of micro-nucleus tested in peripheral blood lymphocytes showed significant increase, and smoking might exert synergetic effect on it. Conclusion it seemed that the slight adverse effects on the workers exposed to low concentration of AN (≤2 mg/m3 MAC) should not be ignored.
出处
《中国职业医学》
CAS
2000年第1期17-19,共3页
China Occupational Medicine
关键词
丙烯腈
流行病学
调查
健康影响
acrylonitrile, health effect, epidemiologic study
