摘要
目的:监测我院7年内阴沟肠杆菌的流行状况和耐药特点,为临床合理使用抗生素提供参考。方法:使用西门子公司的Microscan Walkaway 40SI全自动微生物鉴定/药敏测试系统进行鉴定和药敏试验。结果:阴沟肠杆菌主要引起呼吸道感染,对亚胺培南的敏感性最高,但近两年出现耐药菌株;对第一代头孢菌素头孢唑啉和广谱青霉素类的耐药率>90%;对头孢哌酮/舒巴坦和哌拉西林/舒巴坦耐药率都在30%左右;对其他抗菌药耐药率>50%。结论:阴沟肠杆菌多重耐药的问题日益严重,应监测其耐药变化趋势,指导临床合理使用抗生素。
Objective To investigate the clinical distribution and drug resistance of Enterobacter cloacae. Method Microscan Walkaway 40SI microbial identification and drug sensitivity analysis system was used to analyze 905 Enterobacter cloacae samples. Results Enterobacter cloacae mainly causes respiratory tract infection, and is sensitive to Imipeneln.The bacteria showed a drug resistance rate as high as 90% - 100% against first generation Cepholoporins and Penicillin antibiotics, about 30% against Cefoperazone/Sulbactam and Piperacillin/Sulbactam, and over 50% against other antibiotics. Conclusion Enterobacter cloacae shows high multi-drug resistance rate, which becomes more and more serious. The trend of drug resistance rate should be monitored, and the rational application of clinic antibiotics should be instructed.
出处
《实用医学杂志》
CAS
北大核心
2012年第6期991-993,共3页
The Journal of Practical Medicine
基金
全军医学科学技术研究"十一五"科技攻关项目(编号:06G038)
关键词
抗药性
微生物
阴沟肠杆菌
耐药性
抗菌药物
Drug resistance, microbial
Enterobacter cloacae
Drug resistance
Antibacterialagents
