摘要
可生物降解长效注射给药系统具有局部注射给药一次后能持续几天甚至几个月释药的特点,日益受到生命科学研究者和临床医生的重视。本文介绍了长效注射给药系统的研发历程、生物降解聚合物的类型与特性以及该剂型的临床应用现况,同时客观评价了可生物降解注射剂的应用前景和存在问题。
Due to the distinctive advantage of drug injection, biodegradable long-action injectable drug delivery sustained-release for several days to months after local system (DDS) has got more and more attention either in the life science or in the clinic. The purpose of this paper is to review the procedure in R&D of the DDS, the styles and specific properties of biodegradable polymers as well as the application of the DDS in clinic. The prospect and the problems in application are evaluated.
出处
《中国医药工业杂志》
CAS
CSCD
北大核心
2012年第3期214-221,共8页
Chinese Journal of Pharmaceuticals
关键词
长效注射给药系统
生物可降解
综述
long-action injectable drug delivery system
biodegradable
review