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可生物降解长效注射给药系统的研究进展 被引量:9

Research and Development of Biodegradable Long-action Injectable Drug Delivery System
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摘要 可生物降解长效注射给药系统具有局部注射给药一次后能持续几天甚至几个月释药的特点,日益受到生命科学研究者和临床医生的重视。本文介绍了长效注射给药系统的研发历程、生物降解聚合物的类型与特性以及该剂型的临床应用现况,同时客观评价了可生物降解注射剂的应用前景和存在问题。 Due to the distinctive advantage of drug injection, biodegradable long-action injectable drug delivery sustained-release for several days to months after local system (DDS) has got more and more attention either in the life science or in the clinic. The purpose of this paper is to review the procedure in R&D of the DDS, the styles and specific properties of biodegradable polymers as well as the application of the DDS in clinic. The prospect and the problems in application are evaluated.
出处 《中国医药工业杂志》 CAS CSCD 北大核心 2012年第3期214-221,共8页 Chinese Journal of Pharmaceuticals
关键词 长效注射给药系统 生物可降解 综述 long-action injectable drug delivery system biodegradable review
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参考文献26

  • 1Senior J,Radomsky M.可注射缓控释制剂[M].1版,郑俊民,译.北京:化学工业出版社,2005:2-3.
  • 2Degim IT,Celebi N.Controlled delivery of peptides andproteins[J].Curr Pharm Des,2007,13(1):99-117.
  • 3蒋蓓琦,陈庆华.Depot作为妇科用药缓控释剂型开发和临床应用进展[J].世界临床药物,2007,28(4):243-247. 被引量:2
  • 4何仲贵.可注射用缓释制剂研究进展[J].中国医药技术与市场,2006,6(5):42-49. 被引量:3
  • 5陈庆华,瞿文.多肽、蛋白质类药物缓释剂型的研究进展[J].中国药学杂志,2000,35(3):147-150. 被引量:41
  • 6Solanki HK,Thakkar JH,Jani GK.Recent advances inimplantable drug delivery[J].Int J Pharm Sci Rev Res,2010,4(3):168-177.
  • 7刘晓华.多肽、蛋白质药物缓释新剂型的研究——醋酸亮丙瑞林微球注射剂[D].上海医药工业研究院硕士学位论文,2002.
  • 8瞿文,陈庆华.黄激素释放激素及其类似物的缓释给药系统[J].中国医药工业杂志,1999,30(4):181-188. 被引量:5
  • 9Kelleher JP,Centorrino F,Albert MJ,et al.Advances inatypical antipsychotics for the treatment of schizophrenia:new formulations and new agents[J].CNS Drugs,2002,16(4):249-261.
  • 10Madsbad S,Kielgast U,Asmar M,et al.An overview ofonce-weekly glucagon-like peptide-1 receptor agonists-available efficacy and safety data and perspectives for thefuture[J].Diabetes Obes Metab,2011,13(5):394-407.

二级参考文献17

  • 1宋谋道,余艺华,张邦华,郝广杰,周庆业,张莹,刘升,肖湘.乳酸、羟基乙酸均聚物及共聚物的合成与结构表征[J].离子交换与吸附,1995,11(3):245-252. 被引量:29
  • 2顾素娟,Irving Sivin,杜明昆,张令德,尹利荣,孟凡,吴嵩龄,王佩珠,高云丽,赫欣,戚丽芳,陈昌榕,刘逸萍,王丹,谢争.Norplant皮下埋植剂使用七年效果[J].中国计划生育学杂志,1996,4(1):15-18. 被引量:14
  • 3陈庆华,瞿文.多肽、蛋白质药物的微球给药系统研究进展[J].国外医学(药学分册),1997,24(3):129-133. 被引量:20
  • 4Sivin I;Moo-Young A.Recent developments in contraceptive implants at the population council[J],2002(01).
  • 5Ahmed A;Greenwood N.Lymphadenopathy following repeated oil-based injections,1973(04).
  • 6Fillicorim.Gonacotropin-release hormone agonists,a guide to use and selection[J],1994(01).
  • 7诸云鸿.生殖药理学,1992.
  • 8顾素娟;杜明昆;左诗慧.皮下埋植避孕,1995.
  • 9Senior J;Radomsky M;郑俊民.可注射缓控释制剂,2005.
  • 10Kun Han,Jeong Sook Park,Youn Bok Chung,Mi Jeong Lee,Dong Cheul Moon,Joseph R. Robinson. Identification of Enzymatic Degradation Products of Luteinizing Hormone Releasing Hormone (LHRH)/[D-Ala6] LHRH in Rabbit Mucosal Homogenates[J] 1995,Pharmaceutical Research(10):1539~1544

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