摘要
建立了毛细管气相色谱法测定盐酸奥普力农中的丙酮、四氢呋喃、乙酸乙酯、甲醇、乙醇、正丁醇和N,N-二甲基甲酰胺7种有机溶剂的残留量。采用INNOWax毛细管色谱柱,FID检测器,程序升温。7种溶剂在一定浓度范围内线性关系良好,回收率为95%～103%,RSD小于2%。
A capillary gas chromatography method was established for the determination of seven residual organic solvents： acetone, tetrahydrofuran, ethyl acetate, methanol, ethanol, n-butanol and N,N-dimethylformamide in olprinone hydrochloride. An INNOWax capillary column was used with FID detector and temperature programmed control. The calibration curves were linear in the measured concentration ranges. The recoveries were 95 % - 103 %, with RSDs less than 2 %.
出处
《中国医药工业杂志》
CAS
CSCD
北大核心
2012年第3期212-213,238,共3页
Chinese Journal of Pharmaceuticals
关键词
盐酸奥普力农
有机溶剂残留
毛细管气相色谱
测定
olprinone hydrochloride
residual organic solvent
capillary gas chromatography
determination
