摘要不明原因发热(fever of unknown origin,FUO),指发热时间持续3周,体温多次〉38.3℃,经过至少1周完整的病史询问、体格检查和常规实验室检查仍不能确诊的情况。发热是由于各种致热源导致前列腺素E2释放,作用于下丘脑,使体温调定点升高,从而出现产热效应。儿童群体还有其特殊性,例如,体温调节不稳定,易受环境及心理因素的影响,高温环境、饮食、剧烈运动、
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