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超声造影判定乳腺癌前哨淋巴结的性质 被引量:12

Contrast-enhanced ultrasonography in qualitative diagnosis of sentinel lymph nodes in patients with breast carcinoma
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摘要 目的探讨超声造影判定乳腺癌腋窝前哨淋巴结(SLN)性质并引导手术活检的可行性。方法对22例乳腺癌患者,先用二维超声成像观察腋窝SLN、并综合评分判断其性质,再于乳晕周围皮下注射造影剂SonoVue,超声观察同侧腋窝SLN造影表现,判定其性质,并用细针穿刺定位引导手术切除活检。将二维超声和CEUS结果与病检结果进行比较分析。结果 22例患者均成功在细针穿刺定位引导下完成手术切除活检。与病理结果相比,二维超声判断SLN的敏感度为87.50%(7/8)、特异度为66.67%(10/15)、准确率为73.91%(17/23);CEUS判定SLN性质的敏感度为100%(8/8)、特异度为93.33%(14/15)、准确率为95.65%(22/23)。结论 CEUS较二维超声能更好地预测SLN的性质,并能定位引导腋窝前哨淋巴结活检。 Objective To investigate the feasibility of detecting sentinel lymph nodes(SLN) and then guiding biopsy in patients with breast carcinoma by CEUS.Methods Characteristics and properties of SLN of 22 patients with breast carcinoma were anazlyzed with 2D ultrasonography firstly.Contrast-media SonoVue were hypodermically injected around the areola of breast,and then homonymic axillary fossa sentinel node were inspected and detected by CEUS.Surgical excision guided by ultrasonography and pathological examination of SLN were executed.Results Surgical excision guided by ultrasonography successed in all 22 cases.Taking pathological result as standards,the sensitivity,specificity,accuracy of identifying SLN with 2D ultrasonography was 87.50%(7/8),66.67%(10/15) and 73.91%(17/23),with CEUS was and 100%(8/8),93.33%(14/15) and 95.65%(22/23),respectively.Conclusion CEUS has a good detection rate and can locate SLN and guide biopsy in patients with breast carcinoma.
作者 张茂春 顾鹏
出处 《中国医学影像技术》 CSCD 北大核心 2012年第3期516-519,共4页 Chinese Journal of Medical Imaging Technology
关键词 超声造影 乳腺肿瘤 淋巴结 活组织检查 Contrast-enhanced ultrasonography Breast neoplasms Lymph nodes Biospy
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参考文献10

  • 1Krag DN,Anderson SJ,Julian TB,et al.Sentinel-lymph-node resection compared with conventional axillary-lymph-node dissec-tion in clinically node-negative patients with breast cancer:Over-all survival findings from the NSABP B-32randomised phase3 trial.Lancet Oncol,2010,11(10):927-933.
  • 2王永胜,左文述,刘娟娟,于志勇,刘岩松,李永清,周正波,刘雁冰,李济宇,赵桐,陈鹏.乳腺癌前哨淋巴结活检替代腋窝清扫术前瞻性非随机对照临床研究[J].外科理论与实践,2006,11(2):104-107. 被引量:32
  • 3张武.浅表淋巴结超声检查及进展[J].中华医学超声杂志(电子版),2008,5(1):10-13. 被引量:35
  • 4洪玉蓉,刘学明,张闻,莫国强,许俊,魏红权.超声造影在浅表淋巴结疾病鉴别诊断中的应用研究[J].中华超声影像学杂志,2006,15(11):849-852. 被引量:77
  • 5Soni NK,Spillane AJ.Experience of sentinel node biopsy alone in early breast cancer without further axillary dissection in patients with negative sentinel node.ANZ J Surg,2005,75(5):292-299.
  • 6Iannace C,Di LL,Lepore M,et al.Prognostic and curative value of sentinel node in breast cancer.A377patients experience.Ann ital Chir,2010,81(2):103-113.
  • 7King TA,Fey JV,van Zee KJ,et al.A prospective analysis of the effect of blue-dye volume on sentinel lymph node mapping success and incidence of allergic reaction in patients with breast cancer.Ann Surg Oncol,2004,11(5):535-541.
  • 8钟丽瑶,周平,李瑞珍,曹泽民,吴君辉.经皮下注射超声造影剂在乳腺癌前哨淋巴结诊断中的价值[J].中华超声影像学杂志,2007,16(9):770-772. 被引量:41
  • 9Wang Y,Wang W,Li J,et al.Gray-scale contrast-enhanced ul-trasonography of sentinel lymph nodes in a metastatic breast cancer model.Acad Radiol,2009,16(8):957-962.
  • 10Sever A,Broillet A,Schneider M,et al.Dynamic visualization of lymphatic channels and sentinel lymph nodes using intrader-mal microbubbles and contrast-enhanced ultrasound in a swine model and patients with breast cancer.J Ultrasound Med,2010,29(12):1699-1704.

二级参考文献28

  • 1王永栋,田绍荣,李松年.超声对乳癌淋巴结转移的探讨[J].中国医学影像技术,1995,11(1):32-34. 被引量:8
  • 2周建桥,詹维伟.彩色多普勒超声在颈部淋巴结疾病诊断中的应用[J].中华超声影像学杂志,2005,14(7):529-532. 被引量:92
  • 3Habal N,Giuliano AE,Morton DL.The use of sentinel lymphadenectomy to identify candidates for postoperative adjuvant therapy of melanoma and breast cancer[J].Semin Oncol,2001,28(1):41-52.
  • 4Schwartz GF,Giuliano AE,Veronesi U,et al.Proceedings of the consensus conference on the role of sentinel lymph node biopsy in carcinoma of the breast[J].Cancer,2002,94(10):2542-2551.
  • 5Lucci A Jr,Keleman PR,Miller C,et al.National practice patterns of sentinel lymph node dissection for breast carcinoma[J].J Am coll Surg,2001,192(4):453-458.
  • 6Grube B J,Rose CM,Giuliano AE.Local management of breast cancer[M]//Harris JR,Lippman ME,Morrow M,et al.Disease of the breast.3rd ed.Philadelphia:Lippincott Williams & Wilkins,2004:745-784.
  • 7Halverson K J,Taylor ME,Perez CA,et al.Regional nodal management and patterns of failure following conservative surgery and radiation therapy for stage Ⅰ andⅡ breast cancer[J].Int J Radiat Oncol Biol Phys,1993,26(4):593-599.
  • 8Shiver S,Cox C,Leight G,et al.Final results of the Department of Defense multicenter breast lymphatic mapping trial[J].Ann Surg Oncol,2002,9(3):248-255.
  • 9van Diest PJ,Torrenga H,Borgestein PJ,et al.Reliability of intraopertive frozen section and imprint cytological investigation of sentinel lymph nodes in breast cancer[J].Histopathology,1999,35(1):14-18.
  • 10Motomura K,Inaji H,Komoike Y,et al.Intraoperative sentinel lymph node examination by imprint cytology and frozen sectioning during breast surgery[J].Br J Surg,2000,87(5):597-601.

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