摘要
目的评价二尖瓣舒张早期血流峰速度E与二尖瓣环舒张早期运动峰速度Em之比(E/Em)诊断心房颤动患者舒张性心力衰竭(DHF)的价值。方法将左心室射血分数(LVEF)正常的98例非瓣膜病心房颤动患者分为DHF组(62例)和非心力衰竭(NHF)两组(36例)。对两组临床资料和超声心动图参数进行比较,应用ROC曲线评价E/Em诊断心房颤动患者DHF的价值。结果与NHF组比较,DHF组年龄更大,合并高血压比例更多,NT-proBNP更高,左心房增大,E峰增高,Em降低,E/Em增高(P<0.001)。E/Em诊断DHF的ROC曲线下面积为0.770(95%CI:0.675～0.865)。以E/Em≥9.50为截点时,诊断DHF的敏感度、特异度、阳性预测值及阴性预测值分别为67.7%、72.2%、71.0%和69.1%。结论 E/Em比值对诊断心房颤动患者DHF具有较好的应用价值。
Objective To observe the diagnostic value of the ratio of early diastolic transmitral velocity to early diastolic mitral annular velocity（E/Em） for diastolic heart failure（DHF） in patients with atrial fibrillation.Methods Patients with nonvalvular atrial fibrillation and normal left ventricular ejection fraction（LVEF） were enrolled in the study,which were classified into DHF group（n=62） and non-heart failure group（NHF group,n=36）.The clinical and echocardiographic data were compared between the two groups.ROC curve was used to assess the value of E/Em for the identification of DHF.Results Compared with NHF group,patients with DHF were older,more had hypertension,higher NT-proBNP,larger left atrial,higher E,lower Em and higher E/Em（P0.001）.Using E/Em for identification of DHF,the area under ROC curve was 0.770（95%CI： 0.675—0.865）.Taking E/Em ≥9.50 as optimal cut-off value,the sensitivity,specificity,positive predictive value and negative predictive value was 67.7%,72.2%,71.0% and 69.1%,respectively.Conclusion E/Em could be useful in identifying DHF in patients with atrial fibrillation.
出处
《中国医学影像技术》
CSCD
北大核心
2012年第3期465-469,共5页
Chinese Journal of Medical Imaging Technology
基金
国家高技术研究发展计划(863计划)项目(2007AA02Z457)
