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儿童炎性肌纤维母细胞肿瘤临床病理特点 被引量：2

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摘要 目的探讨儿童炎症性肌纤维母细胞性肿瘤(inflam-matory myofibroblastic tumor,IMT)的临床、病理学特点及鉴别诊断。方法对3例儿童IMT进行了组织形态学、免疫组化检查,结合文献复习进行分析并随访。结果其中例1、2症状均为反复咳嗽、发热、呼吸困难,年龄分别为8岁、5岁,胸片均为支气管旁实性肿块。例3年龄为11岁,因乏力、食欲不振、贫血就诊,B超示盆腔实质性肿块。镜下可见肿瘤由肌纤维母细胞性梭形细胞、浆细胞、淋巴细胞、嗜酸性粒细胞等炎症细胞构成。免疫表型:梭形细胞胞质内vimentin、desmin、MSA、SMA灶性或弥漫性阳性,myogenin、myoglobin、S-100和CD117为阴性,其中1例ALK阳性。结论 IMT是一种罕见的中间型肿瘤,原发于儿童和青少年的软组织和内脏,需与肉芽组织、结节性筋膜炎、平滑肌瘤、纤维组织细胞瘤或韧带样型纤维瘤病等鉴别。
作者 王雪莉 史青 孙和国 奚政君 张彬
机构地区 上海市儿童医院 上海交通大学附属儿童医院 上海市吴淞中心医院病理科
出处 《临床与实验病理学杂志》 CAS CSCD 北大核心 2012年第3期336-338,共3页 Chinese Journal of Clinical and Experimental Pathology
关键词 炎症性肌纤维母细胞性肿瘤 儿童 鉴别诊断
分类号 R732.1 [医药卫生—肿瘤]
  • 相关文献

参考文献13

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二级参考文献36

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共引文献46

同被引文献27

  • 1李正江,唐平章,徐震纲.颈段气管肿瘤的诊治经验[J].中华耳鼻咽喉头颈外科杂志,2006,41(3):208-210. 被引量：17
  • 2朱巧洪,曾庆思,关玉宝.原发性气管肿瘤的多层螺旋CT诊断[J].中国医学影像学杂志,2006,14(2):97-100. 被引量：12
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引证文献2

二级引证文献6

临床与实验病理学杂志
2012年 第3期

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