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大剂量尿激酶静脉溶栓治疗急性心肌梗塞的临床观察

The clinical Observation of Hyper dose Urokinase Thrombolytic Therapy in Acute Myocardial Infarction
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摘要 用大剂量尿激酶(UK)静脉溶栓(进口UK50万U静推5~15分钟,100万U静点30分钟或国产UK100万U静推5~15分种,100万U静点30分钟滴完)治疗30例发病6小时内急性心肌梗塞(AMI),根据临床冠脉再通指标观察再通率为96.7%(29/30),明显高于UK50~150万U/60~90分种静脉溶栓再通率(50%~55%),亦与rt-PA、SK加速溶栓治疗的结果相一致。无脑出血及严重内脏出血。大剂量UK静脉溶栓治疗AMI是一种安全有效的方法,值得进一步研究和推广。 Thirty seven patients with acute myocardial infarction within 6hours after onset of symptoms were used with hyper dose urokinase (UK 150 ~ 200 million U) thrombolytic therapy intrvenously. The reperfusion rate of infarct - related arteries determined by clinical evidence of reperfusion was 96. 7% (29/30) , which was higher obviously than the reperfusion rate of UK 50 ~ 150 million U/60 - 90min thrombolytic intrvenously, without encephalorrhagia and internal organs serious bleeding complications. It is safe and effective that hyper dose urokinase thrombolytic therapy in acute myocardial infarction.
出处 《医学研究通讯》 2000年第2期43-44,共2页 Bulletin of Medical Research
关键词 心肌梗塞 尿激酶 AMI 药物疗法 静脉溶栓 Myocardial infarction Urodinase
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