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595nm脉冲染料激光治疗鲜红斑痣1560例临床研究 被引量:15

Flashlamp-pumped pulsed dye laser (595 nm) for the treatment of port-wine stains: a clinical review of 1560 patients
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摘要 目的评价595nm脉冲染料激光治疗不同年龄段鲜红斑痣患者的临床疗效和不良反应。方法应用美国Candela公司生产的595nm脉冲染料激光治疗鲜红斑痣1560例,根据患者年龄、皮损类型等采用不同参数进行激光照射治疗。结果595nm脉冲染料激光治疗鲜红斑痣总有效率为76.73%(1197/1560),疗效与患者年龄、皮损类型等因素关系密切,不良反应发生率低,且耐受性好。结论595nm脉冲染料激光治疗鲜红斑痣安全有效。 Objective To evaluate the efficacy and safety of a 595-nm flashlamp-pumped pulsed dye laser in the treatment of patients at different ages with port-wine stains (PWS). Methods A retrospective re- view was performed in 1560 patients with PWS who had been treated with a 595-nm flashlamp-pumped pulsed dye laser. Treatment parameters were selected according to the age of and types of lesions in patients. Results The total response rate was 76.73% (1197/1560) in all of the patients. Clinical efficacy of the flashlamp- pumped pulsed dye laser was closely correlated with patients'age (X2 = 83.47, P 〈 0.01 ) and types of lesions (X2 = 46.30, P 〈 0.01 ). There was a low incidence of adverse reactions which were well tolerable. Conclusion The 595-nm flashlamp-pumped pulsed dye laser is safe and effective for the treatment of PWS.
出处 《中华皮肤科杂志》 CAS CSCD 北大核心 2012年第3期201-202,共2页 Chinese Journal of Dermatology
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参考文献7

  • 1Goh CL. Flashlamp-pumped pulsed dye laser (585 nm) for the treatment of portwine stains--a study of treatment outcome in 94 Asian patients in Singapore. Singapore Med J, 2000, 41 ( 1 ): 24- 28.
  • 2Garden JM, Tan OT, kerschmanm R, et al. Effect of dye laser pulse duration on selective cutaneous vascular injury. J Invest Dermatol, 1986, 87(5): 653-657.
  • 3Kimel S, Svaasand LO, Cao D, et al. Vascular response to laser photothermolysis as a function of pulse duration,vessel type, and diameter: implications for port wine stain laser therapy. Lasers Surg Med, 2002, 30(2): 160-169.
  • 4Goldman MP, Fitzpatrick RE, Ruiz-Esparza J. Treatment of port wme stains (capillary malformation) with the flashlamp-pumped pulsed dye laser. J Pediatr, 1993, 122( 1 ): 71-77.
  • 5邓波,谢红付,刘稚然.脉冲染料激光治疗155例鲜红斑痣患者临床疗效观察[J].中华皮肤科杂志,2000,33(6):429-429. 被引量:7
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二级参考文献2

  • 1Seukeran DC,Collins P,Sheehan Dare RA.Adverse reactions following pulsed tunable dye laser treatment of port wine stains in 701 patients[].Br J Dermatol.1997
  • 2Gaston DA,Clark DP.Facial hypertrophic scarring from pulsed dye laser[].Dermatologic Surgery.1998

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